Nosocomial infections: urinary tract infection in patients with indwelling urinary catheter

Catheter associated urinary tract infection: Aetiologic agents and antimicrobial susceptibility pattern in Ladoke Akintola University Teaching Hospital, Osogbo, Nigeria

“…The mean age of patients in this study is 66 years and the age group 61-70 years constitutes the largest group (39.3%) while over 90% of the patients were above 50 years of age. This finding agrees with a previous study (Oni et al, 2003) in another institution located in the same geographical zone as ours. Males were also predominantly affected in our study.…”

“…This calls for reassessment of the rational for prophylactic antibiotic use after catheterization. Several other studies (Turck et al, 1962;Kass, 1956;Kunin and McCormack, 1966;Garibaldi et al, 1974;Britt et al, 1977;Oni et al, 2003) have shown antibiotic prophylaxis to be ineffective and rather lead to emergence of resistant pathogens as evidenced in this study.…”

“…This is the pattern of distribution seen in most studies (Selden et al, 1971;McLeod 1958;Oni et al, 2003) . Many of these pathogens are part of the patients' endogenous bowel flora but some may have been acquired by cross-contamination from other patients or hospital personnel or by exposure to contaminated solutions or non-sterile equipment.…”

“…The last complication is serious since it is associated with a significant mortality but fortunately occurs in less than 1% of catheterized patients (Steere et al, 1979;Kreger et al, 1980). Although community acquired UTI has been well investigated in different groups of patients in Nigeria (Akinkugbe et al, 1973;Ekweozor and Onyemenem, 1996;Odutola et al, 1998), only few studies (Oni et al, 2003) have investigated and documented the aetiological agents of catheter-associated UTI or their susceptibility pattern to antimicrobial agents. In our institution, catheterization is a frequent procedure performed for patients with urinary tract obstructive lesions such as benign prostatic hyperplasia who are awaiting surgery and also as a routine in the management of unconscious patients to monitor their urine output.…”

Microbiological assessment of indoor air of a teaching hospital in Nigeria

“…compromised patients [24,25] , though not isolated from any of the patients on admission during the study, (surveillance report) their isolation in this study calls for more adequate control measures. The isolation of Aspergillus flavus, a medically important fungus for aflatoxin production, a neurotoxigenic substance, and which can also cause lung infection should not be overlooked just as Candida albicans which are isolated from the neonatal wards where they can cause neonatal conjunctivitis.…”