2000
DOI: 10.1086/501795
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Nosocomial Infections in Combined Medical-Surgical Intensive Care Units in the United States

Abstract: Nosocomial infections in MS ICUs at the most frequent infection sites (bloodstream, urinary, and respiratory tract) almost always were associated with use of an invasive device. Device-associated infection rates were the best available comparative rates between combined MS ICUs, but the distribution of device-associated rates should be stratified by a hospital's major teaching affiliation status.

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Cited by 875 publications
(582 citation statements)
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“…It is likely that more severely ill neonates required the use of both a ventilator and a catheter, but unmeasured factors such as preexisting colonization of the respiratory tract with potential pathogens may have increased the risk for CR BSI, as has been noted for candidemia. 24,25 In this study population, CR BSI were more likely than non-CR BSI to be caused by grampositive than gram-negative organisms. Gram-positive skin flora may be more likely to colonize the catheter during catheter insertion and use, whereas infections with gram-negative organisms may be more commonly associated with translocation of flora from the gut or respiratory or urinary tract.…”
Section: Discussionmentioning
confidence: 86%
“…It is likely that more severely ill neonates required the use of both a ventilator and a catheter, but unmeasured factors such as preexisting colonization of the respiratory tract with potential pathogens may have increased the risk for CR BSI, as has been noted for candidemia. 24,25 In this study population, CR BSI were more likely than non-CR BSI to be caused by grampositive than gram-negative organisms. Gram-positive skin flora may be more likely to colonize the catheter during catheter insertion and use, whereas infections with gram-negative organisms may be more commonly associated with translocation of flora from the gut or respiratory or urinary tract.…”
Section: Discussionmentioning
confidence: 86%
“…It is also one of the most common causes of infections in patients in intensive care [44,53], with nosocomial bloodstream infections [37], and with healthcare-associated pneumonia [35,50]. S. aureus is a Gram-positive aerobic bacteria often found in normal skin flora [31].…”
Section: Introductionmentioning
confidence: 99%
“…15.0% for P.aeruginosa 9.5% and 24.4% for MRSA [13]. Bacteriuria in long -term catheterized patients is usually polymicribial and, in addition to the pathogens seen in short-term catheterized patients.…”
Section: Uropathogensmentioning
confidence: 99%