2012
DOI: 10.1590/s0037-86822012005000003
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Nosocomial infections in a pediatric intensive care unit of a developing country: NHSN surveillance

Abstract: Introduction: This study aimed to determine the epidemiology of the three most common nosocomial infections (NI), namely, sepsis, pneumonia, and urinary tract infection (UTI), in a pediatric intensive care unit (PICU) in a developing country and to define the risk factors associated with NI. Methods: We performed a prospective study on the incidence of NI in a single PICU, between August 2009 and August 2010. Active surveillance by National Healthcare Safety Network (NHSN) was conducted in the unit and in a ca… Show more

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Cited by 38 publications
(31 citation statements)
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References 38 publications
(60 reference statements)
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“…Henderson et al showed that Gram-positive pathogens were considerably more common among pediatric patients with bacteremia in England and Wales, with the most common Gram-negative pathogens being E. coli and Neisseria meningitidis, which accounted for only 5% of infections each (11). In a pediatric intensive care unit (ICU) in Brazil, however, Gram-negative pathogens accounted for the largest proportion of infections (47%) among cases of sepsis, pneumonia, and urinary tract infections, with E. coli and Enterococcus faecalis being the most common pathogens encountered (18% each) (12). An even more dramatic difference was observed among nosocomial infections (NIs) in a general pediatric hospital in Turkey, where Gram-negative pathogens accounted for 79.8% of cultured pathogens among 229 NIs; the most common pathogens identified were Klebsiella spp.…”
Section: Discussionmentioning
confidence: 99%
“…Henderson et al showed that Gram-positive pathogens were considerably more common among pediatric patients with bacteremia in England and Wales, with the most common Gram-negative pathogens being E. coli and Neisseria meningitidis, which accounted for only 5% of infections each (11). In a pediatric intensive care unit (ICU) in Brazil, however, Gram-negative pathogens accounted for the largest proportion of infections (47%) among cases of sepsis, pneumonia, and urinary tract infections, with E. coli and Enterococcus faecalis being the most common pathogens encountered (18% each) (12). An even more dramatic difference was observed among nosocomial infections (NIs) in a general pediatric hospital in Turkey, where Gram-negative pathogens accounted for 79.8% of cultured pathogens among 229 NIs; the most common pathogens identified were Klebsiella spp.…”
Section: Discussionmentioning
confidence: 99%
“…Full-text articles were retrieved for 46 abstracts and further reviewed for eligibility by both authors, after which 12 articles met our inclusion criteria and were appropriate for in-depth assessment (Table 1) . These were 11 observational and one case-control study citations describing acquired infection and mortality rates, as well as epidemiology of Gramnegative infections, in Latin American PICUs and NICUs [9][10][11][12][13][14][15][16][17][18][19][20]. The studies varied widely with respect to location, time period, patient population, design, and data reporting, which prevented inter-study comparisons.…”
Section: Selected Studiesmentioning
confidence: 99%
“…Eight of the 12 studies reported data regarding acquired infection and mortality rates ( Table 2) [9][10][11]14,[16][17][18][19]. The infection rate (35% to 37% vs ≤ 24%) and incidence rate (58% vs ≤ 20%) was highest in studies enrolling significant proportions of extremely low-birth-weight infants, as evidenced by data from a 10-year prospective follow-up study and a 3-year retrospective study, both of which were conducted in Brazil [10,19].…”
Section: Clinical Epidemiologymentioning
confidence: 99%
“…Результаты других аналогичных исследований указывают на респираторные инфекции и инфекции уретрального трака [15][16].…”
Section: Discussionunclassified