Nosocomial infections and hospital deaths

Hospital-Acquired Infective Endocarditis

“…The mean age of patients with nosocomial endocar¬ ditis in previous studies also was older than that of patients acquiring endocarditis out of hospital.6·7 As the population ages, with increased use of hospital beds by the elderly, the risks for nosocomial infections, including endocarditis, in the older age groups may increase still further. 13 Overall, endocarditis is now more prominent as a disease of the elderly than was previously noted.8·1014 Endocarditis, whether hospital or community acquired, is associated with more diagnostic difficulties and a higher mortality rate in elderly patients than in younger patients.8 One half of our elderly patients with nosocomial endocarditis died, and these patients constituted 77.8% of all deaths caused by nosocomial endocarditis in our series.…”

Ventilator-associated pneumonia is an important risk factor for mortality after major cardiac surgery

“…Previous studies have reached conflicting conclusions regarding the impact of VAP on mortality [1,[8][9][10][11][12][13][14][15][16][17]. Although the gross mortality rate is high, there are doubts as to whether the higher mortality rate is due to VAP itself or to the seriousness of the underlying illness.…”

Infecção hospitalar e mortalidade

“…Porém, Wenzel (25) cita estudos de caso-controle pareados para estimar a mortalidade atribuível as infecções de corrente sangüínea que mostram uma variação de 21,0% a 31,0% . Outros estudos em UTIs obtiveram valores superiores a 40,0% (26)(27) Salemi (28) (11) , em estudo realizado, com cem mortes consecutivas pareadas com cem sobreviventes, no Hackensack Medical Center (Estados Unidos), em 1978 e 1979, demonstraram que a morte esteve mais associada com a gravidade da doença de base à admissão do que com a infecção hospitalar nos casos e controles. Os pacientes com doença terminal não mostraram diferença estatisticamente significativa quanto à presença de infecção hospitalar nos casos e nos controles.…”