Nosocomial Infection Caused by Antibiotic-Resistant Organisms in the Intensive-Care Unit

Flaherty, John P.; Weinstein, Robert A.

doi:10.1086/647287

Cited by 59 publications

(26 citation statements)

References 143 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Such differences have been well described, and a number of reports have been published that point out potential pitfalls of combining all tested isolates into one hospitalwide antibiogram. [13][14][15] Several studies have illustrated differences between antibiograms reflecting isolates from patients in ICUs to hospitalwide versions. [16][17][18][19] Our results are consistent with this observation.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Hospitalwide and Custom Antibiograms for Clinical Isolates of Pseudomonas aeruginosa

2013

View full text Add to dashboard Cite

Background: Hospital antibiograms, which are commonly used to determine empiric antibiotic therapy and as a tool in stewardship in a given institution, are open to bias when combining susceptibility results from various sources, hospital locations, and patient groups. Methods: We assessed such differences, using Pseudomonas aeruginosa as a test case, with susceptibility data from 2008 through 2010 in our institution. Each year's data were analyzed separately. A variety of specific or subcategorical antibiograms were compared with each other as well as with versions including all tested isolates and those with results from inpatients and outpatients only. Statistical significance was determined at the .01 level using either chi-square or Fisher exact test, and clinical significance was defined as $10 percentage points. Results: A variety of clinically significant differences were found that illustrated important differences within the intensive care unit environment and based on population, specifically adult versus pediatric. Concordance between statistically significant and clinically significant differences was poor. Conclusion These results corroborate and extend previous similar observations and point to the potential importance of subanalyses in preparing the annual hospital antibiogram.

show abstract

Section: Discussionmentioning

confidence: 99%

Comparison of Hospitalwide and Custom Antibiograms for Clinical Isolates of Pseudomonas aeruginosa

2013

View full text Add to dashboard Cite

show abstract

“…Spread of MRSA has been associated with hospital hygiene, control and prevention. There are three major modes of transmission of micro-organism: person-toperson spread, direct or indirect contact transmission on the hands of health-care workers [7] and contaminated environmental surfaces or devices [7,11]. The contribution of contaminated environmental surfaces to transmission of MRSA however, is controversial.…”

Section: Review and Description Of The Datamentioning

confidence: 99%

Smoothing a discrete hazard function for the number of patients colonized with Methicillin‐resistant Staphylococcus Aureus in an intensive care unit

Ismail

Pettitt

2004

Statistics in Medicine

View full text Add to dashboard Cite

A new method for estimating the time to colonization of Methicillin-resistant Staphylococcus Aureus (MRSA) patients is developed in this paper. The time to colonization of MRSA is modelled using a Bayesian smoothing approach for the hazard function. There are two prior models discussed in this paper: the first difference prior and the second difference prior. The second difference prior model gives smoother estimates of the hazard functions and, when applied to data from an intensive care unit (ICU), clearly shows increasing hazard up to day 13, then a decreasing hazard. The results clearly demonstrate that the hazard is not constant and provide a useful quantification of the effect of length of stay on the risk of MRSA colonization which provides useful insight.

show abstract

“…Hastanede yatan hastalarda, invazif alet kullanımının artması, konak savunma mekanizmalarının bozulması, altta yatan hastalıklar ve geniş spektrumlu antimikrobiyal kullanımına bağlı olarak sağlık bakımıyla ilişkili infeksiyonlar daha sık görülmektedir (1,2).…”

Section: Introductionunclassified

Catheter-Associated Urinary Tract Infections

Keten¹,

Aktaş²

2015

Klimik Dergisi

View full text Add to dashboard Cite

ÖzetHastanede yatan hastalarda, invazif alet kullanımının artması, bozulmuş konak savunma mekanizmaları, altta yatan hastalıklar ve geniş spektrumlu antimikrobiyal kullanımına bağlı olarak, sağlık bakımıyla ilişkili infeksiyonlar daha sık görülmektedir. Sondayla ilişkili üriner sistem infeksiyonlarına neden olan mikroorganizmalar, sıklıkla endojen floradan kaynaklanmaktadır. Bu patojenler hastanın (kolon, vagina, meatus vb.) kendi florasından kaynaklanabileceği gibi, hastanede yatan olgularda sağlık çalışanlarının elleri veya kontamine aletlerle de bulaşma söz konusu olabilmektedir. Uygulanacak sondaların özellikleri, uygulama koşulları, uygulama sonrası bakım ve uygulamayı yapanların bilgi düzeyi, sondaya bağlı infeksiyon geliş-me riskini etkilemektedir. Bu yazıda sondayla ilişkili üriner sistem infeksiyonlarının, epidemiyolojisi, etyolojisi, patogenezi, risk faktörleri, sonda uygulamalarının çeşitleri, tanısı, tedavisi, prognozu ve önlen-mesi gözden geçirilmiştir. Klimik Dergisi 2014; 27(2): 38-47.Anahtar Sözcükler: Üriner sistem infeksiyonları, üriner sonda kullanımı, üriner sondayla ilişkili infeksiyonlar. AbstractHealthcare-associated infections are more frequently seen in hospitalized patients due to increased use of invasive techniques, impaired host immune system, comorbidities, and use of broad-spectrum antibiotics. Microorganism causing catheter-associated urinary tract infections may arise from patients' endogenous flora (colon, vagina, meatus etc.) or from contamination by staff during instrumentation. The risk of catheter-associated urinary tract infections are affected by properties of catheters, conditions of practice, post-practice care, and experience of the practitioner. This review outlines the epidemiology, etiology, pathogenesis, risk factors, catheterization techniques, diagnosis, therapy and prognosis of catheter-associated urinary tract infections, and preventive measures against these infections.

show abstract

Nosocomial Infection Caused by Antibiotic-Resistant Organisms in the Intensive-Care Unit

Cited by 59 publications

References 143 publications

Comparison of Hospitalwide and Custom Antibiograms for Clinical Isolates of Pseudomonas aeruginosa

Comparison of Hospitalwide and Custom Antibiograms for Clinical Isolates of Pseudomonas aeruginosa

Smoothing a discrete hazard function for the number of patients colonized with Methicillin‐resistant Staphylococcus Aureus in an intensive care unit

Catheter-Associated Urinary Tract Infections

Contact Info

Product

Resources

About