Nosocomial Bacteremia Caused by Biofilm-Forming Bacillus cereus and Bacillus thuringiensis

Bacillus amyloliquefaciens bacteriemia in two preterm neonates: A significant catheter-related invasive infection in neonates

“…Bacillus amyloliquefaciens, a gram-positive, rod-shaped, oval spore forming, aerobe bacterium of the family Bacillaceae, that is found commonly in soil, air [6], food, such as dried milk products [7], and many other sources, is the main strain implicated in production of α-amylase and protease [8,9]. Few studies also described this organism found on the hands of nursing staff or alcoholic preparation [10]. Also known for his use in biocontrol products [11,12] and probiotics [13], Bacillus amyloliquefaciens is not known as a human pathogen but, in recent years, there has been an increasing appreciation for the potential of Bacillus as opportunistic pathogens in immune-compromised [6,14] or otherwise critically ill patients, those with foreign bodies [15] and intravenous drug abusers as seen with B. cereus [16,17], B. thuringiensis [10] and B. anthracis [18].…”

“…Few studies also described this organism found on the hands of nursing staff or alcoholic preparation [10]. Also known for his use in biocontrol products [11,12] and probiotics [13], Bacillus amyloliquefaciens is not known as a human pathogen but, in recent years, there has been an increasing appreciation for the potential of Bacillus as opportunistic pathogens in immune-compromised [6,14] or otherwise critically ill patients, those with foreign bodies [15] and intravenous drug abusers as seen with B. cereus [16,17], B. thuringiensis [10] and B. anthracis [18]. Some gastrointestinal infections are also reported with Bacillus species [19,20].…”

“…An antibiogram was made and revealed that the pathogen had no resistance to any of those antibiotics despite an increased number of resistance to vancomycin described in the literature [25]. Bacillus species are also able to form biofilm which could help them to survive in a hospital environment, which lead us to be even more careful about these therapies [10]. To add with that, Bacillus species can easily adhere to the surface of catheter and this property makes central catheter withdrawal primordial to be as efficient as possible.…”

Use of Peripheral Parenteral Nutrition Solutions as a Risk Factor for <i>Bacillus cereus</i> Peripheral Venous Catheter-Associated Bloodstream Infection at a Japanese Tertiary Care Hospital: a Case-Control Study

“…However, outbreaks of catheter-related bloodstream infection (CRBSI) have been sporadically reported in association with a specific hospital environment or linens (9)(10)(11)(12)(13)(14)(15)(16)(17). Multiple fatal cases with serious B. cereus CRBSI were recently reported (3,6,(13)(14)(15)17).…”

Late Prosthetic Joint Infection and Bacteremia by Bacillus cereus Confirmed by 16S rRNA Sequencing and Hip Joint Tissue Pathology

“…B. cereus rarely causes severe infections such as bacteremia or endocarditis and most of them are central line-related infections [2]. B. cereus from blood has been easily dismissed as a contaminant without repeated blood isolation from multiple cultures.…”