Northern light reviews – Application of orthodoxy and network biology to infer gene functions in non‐model plants
Klaas Vandepoele,
Sander Thierens,
Michiel Van Bel
Abstract:Approximately 60% of the genes and gene products in the model species Arabidopsis thaliana have been functionally characterized. In non‐model plant species, the functional annotation of the gene space is largely based on homology, with the assumption that genes with shared common ancestry have conserved functions. However, the wide variety in possible morphological, physiological, and ecological differences between plant species gives rise to many species‐ and clade‐specific genes, for which this transfer of k… Show more
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