Normal Variations of the Inorganic Phosphate of Blood

Havard, R. E.; Reay, G. A.

doi:10.1042/bj0190882

Cited by 42 publications

(7 citation statements)

References 2 publications

(1 reference statement)

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“…Diurnal fluctuations in serum phosphate concentrations occur with phosphate concentration being lowest in the early morning but increasing by 16% by midday (Havard and Reay, 1925). During an evening sleep cycle, phosphate increases by approximately 40%, remains elevated, then drops rapidly after awakening (Havard and Reay, 1925). There are also seasonal variations with phosphate concentrations being higher in the summer than in the winter (Havard and Reay, 1925).…”

Section: Factors Affecting Phosphate Homoeostasismentioning

confidence: 99%

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Hyperphosphatemia Management in Patients with Chronic Kidney Disease

Shaman

Kowalski

2016

Saudi Pharmaceutical Journal

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Hyperphosphatemia in chronic kidney disease (CKD) patients is a potentially life altering condition that can lead to cardiovascular calcification, metabolic bone disease (renal osteodystrophy) and the development of secondary hyperparathyroidism (SHPT). It is also associated with increased prevalence of cardiovascular diseases and mortality rates. To effectively manage hyperphosphatemia in CKD patients it is important to not only consider pharmacological and nonpharmacological treatment options but also to understand the underlying physiologic pathways involved in phosphorus homoeostasis. This review will therefore provide both a background into phosphorus homoeostasis and the management of hyperphosphatemia in CKD patients. In addition, it will cover some of the most important reasons for failure to control hyperphosphatemia with emphasis on the effect of the gastric pH on phosphate binders efficiency.

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Section: Factors Affecting Phosphate Homoeostasismentioning

confidence: 99%

“…During an evening sleep cycle, phosphate increases by approximately 40%, remains elevated, then drops rapidly after awakening (Havard and Reay, 1925). There are also seasonal variations with phosphate concentrations being higher in the summer than in the winter (Havard and Reay, 1925).…”

Section: Factors Affecting Phosphate Homoeostasismentioning

confidence: 99%

Hyperphosphatemia Management in Patients with Chronic Kidney Disease

Shaman

Kowalski

2016

Saudi Pharmaceutical Journal

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“…Taking cultivated pasture as a standard, the basal ration is, thus, very deficient in lime. The basal ration is also estimated to be deficient in N and Cl, and to contain an excess of P o 0 6 The chlorine deficiency was corrected by the provision of salt licks, but the N deficiency was not corrected. The effect of this N deficiency will be reported in a separate communication.…”

mentioning

confidence: 99%

The Effect of Lime and Cod-Liver Oil on Sheep Fed on a Calcium Deficient Ration

Auchinachie¹,

Fraser²

1932

J. Agric. Sci.

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“…Seasonal variation in the inorganic phosphate concentration of blood was first noted by Hess & Lundagen (1922) in children and by Havard & Reay (1925) in adults. Since the level of inorganic phosphate in the blood of infants could be raised by frequent exposure to ultra-violet light (Hess & Gutman, 1921), it was concluded that the increase in the blood-phosphate level in summer and the decrease in winter were related to seasonal variations in the intensity of ultra-violet light.…”

mentioning

confidence: 99%