Normal Values of Lower Limb Nerve Conduction in Kuwait

Abstract

Objectives: To establish the normal electrophysiological values of the common lower limb nerves and to study the relationship of conduction velocity (CV) of the lower limb nerves to height and age in healthy adult subjects. Methods: Nerve conduction investigations were performed on the lower limbs of 51 screened healthy volunteers using standard electrophysiological techniques. Results: Fifty-one subjects (21 males and 30 females) participated in the study. The mean (± SD) ages of the subjects were 38 (±8.82) and 36 (±8.58) years for males and females, respectively. The tibial motor nerve showed a mean (± SD) CV of 46.1 (±3.3) m/s, distal latency (DL) 4.4 (±0.8) ms, and amplitude 8.8 (±3.4) mV for males. For females, the results were CV 47.8 (±3.4) m/s, DL 3.9 (±0.85) ms and amplitude 12.0 (±3.4) mV. Peroneal motor parameters were CV 47.1 (±3.3) m/s, DL 3.9 (±0.53) ms, amplitude 5.6 (±2.2) mV for males and 49.3 (±2.3) m/s, 4.0 (±0.56) ms, 6.0 (±2.2) mV for females, respectively. The sural sensory nerve parameters were CV 48.7 ± 6.0 m/s, DL 2.9 (±0.3) ms, amplitude 18.9 (±3.3) μV for males and 51.5 (±4.9) m/s, 2.7 (±0.24) ms and 21.6 (±6.3) μV for females. Most CV values were significantly correlated with height, and there was a significant difference between males and females. However, after adjustment for height by the linear regression method, all significant gender differences disappeared. Conclusion: This study established the normative conduction parameters of the commonly tested nerves of the lower limbs for our electromyography laboratory in Kuwait. Gender differences disappeared when the data were adjusted for age and height.

Prospective Evaluation of the Effect of Short-Term Oral Vitamin D Supplementation on Peripheral Neuropathy in Type 2 Diabetes Mellitus

“…The secondary outcome measure was the assessment of neuropathy by means of an NCS, performed on all patients using established, standard techniques [ 12 , 13 ]. Measurements of latencies, amplitudes and conduction velocities were evaluated using previously established cut-off values, for the motor (peroneal, tibial, median and ulnar) and sensory (sural, median and ulnar) nerves [ 3 , 14 , 15 ].…”

Does Vitamin D deficiency play a role in peripheral neuropathy in Type 2 diabetes?

“…The values for the NCS scored 0 for normal and 1 for abnormal. The cut‐off values used for individual nerves were established and published previously [10,11]. The normal range used for NCS was the mean reference values ± 2 standard deviations.…”

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“…3,11,21 Most of our values were similar to four other similar published studies. 2,3,5,8,13,21,22,23 However, there were some differences, which could be attributed to different NCS techniques, machine settings, and demographic characteristics. A notable dissimilarity was in the CMAP and the SNAP amplitudes because some studies used peak-to-peak measurement and others used baseline-to-negative peak measurements.…”

“…NCS data interpretation is influenced by some technical and physiological factors, such as fixed measurements, skin temperature, height, Body Mass Index (BMI), gender and age; In addition to the nerve diameter and degree of myelination. 2,3,[5][6][7][8] It is clearly required, in a clinical setting, to have standardized data acquired from a sample population that represents, as nearly as possible, the demographic and ethnic features of the examined patients. 2,3 In the context of developing normative data for nerve conduction studies among healthy Omani adults for our Neurophysiology laboratory, we aimed also to examine the influence of gender on our data.…”