Normal left atrial function determined by 2-dimensional echocardiography

Gutman, Jack; Wang, Yin Shi; Wahr, Dennis; Schiller, Nelson B.

doi:10.1016/s0002-9149(83)80061-7

Cited by 135 publications

(71 citation statements)

References 28 publications

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“…Left atrial maximum and minimum areas, maximum and minimum long diameters at mitral valve opening and mitral valve closure were measured from apical views (Gutman et al 1983;Basnight et al1991). Left atrial maximum and minimum volumes (LAV max and LAV min ) were determined from orthogonal apical views using the biplane area-length method (Fig.…”

Section: Echocardiographymentioning

confidence: 99%

Effect of Cardiac Resynchronization Therapy on Left Atrial Reverse Remodeling and Spontaneous Echo Contrast

Vural

Ağaçdiken

Ural

et al. 2004

Tohoku J. Exp. Med.

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Recent studies revealed reverse remodeling in left ventricle with cardiac resynchronization therapy (CRT). However, effects on left atrial remodeling, left atrial total emptying fraction and left atrial spontaneous echo contrast (SEC) have not been adequately evaluated. The aim of this study was to investigate the long-term changes in SEC, left atrial reverse remodeling, and left atrial total emptying fraction after CRT. Twenty patients with systolic heart failure and complete left bundle-branch block underwent implantation of biventricular pacemaker devices. Transthoracic and transesophageal echocardiography were performed one week before and one and six months after pacemaker implantation. After biventricular pacemaker implantation, significant clinical improvement was observed in all patients. Left atrial maximal and minimal volumes showed a significant progressive decline after CRT (reverse remodeling). Left atrial total emptying ejection fraction (LATEF) was 33±19% at baseline and increased to 37±10% and 41±11% at the 1st and 6th months respectively (p=0.01 and p=0.04). SEC was detected in 18 of 20 patients (90%) at the beginning of the study. After six months SEC disappeared in 5 patients and frequency of SEC reduced to 45%. Decrease in the intensity of the SEC was also statistically significant (at the 1st and 6th months; p=0.001 and p<0.001 respectively). Long-term CRT results in atrial reverse remodeling, increases LATEF, and reduces both frequency and intensity of atrial SEC. cardiac resynchronization; atrial reverse remodeling; SEC

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Section: Echocardiographymentioning

confidence: 99%

Effect of Cardiac Resynchronization Therapy on Left Atrial Reverse Remodeling and Spontaneous Echo Contrast

Vural

Ağaçdiken

Ural

et al. 2004

Tohoku J. Exp. Med.

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“…Two-dimensional (D) echocardiography-derived LA volume has been shown to provide a more accurate assessment of LA size than the M-mode LA dimension. [3][4][5][6][7][8] Recent studies demonstrated that the LA volume was more strongly associated with the future development of atrial fibrillation than LA dimension. 9,10 The LA volume was also strongly associated with the prognosis of patients with acute myocardial infarction 11 and dilated cardiomyopathy.…”

mentioning

confidence: 99%

“…9,10 The LA volume was also strongly associated with the prognosis of patients with acute myocardial infarction 11 and dilated cardiomyopathy. 12 Methods to calculate LA volume have been described, [3][4][5][6] but the distribution of LA volume in normal Japanese subjects who do not have cardiovascular disease has not been reported. Our objective was to provide reference ranges of the LA volume in healthy Japanese adults.…”

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confidence: 99%

Left Atrial Volume in Normal Japanese Adults

Yamaguchi¹,

Tanabe²,

Tani³

et al. 2006

Circ J

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eft atrial (LA) enlargement is associated with cardiovascular disease and is a risk factor for atrial fibrillation, stroke, and death. 1,2 However, LA antero-posterior dimensions have well-known limitations for indicators of chamber size, for example, the left ventricular (LV) dimension is a poor indicator of LV volume. Two-dimensional (D) echocardiography-derived LA volume has been shown to provide a more accurate assessment of LA size than the M-mode LA dimension. [3][4][5][6][7][8] Recent studies demonstrated that the LA volume was more strongly associated with the future development of atrial fibrillation than LA dimension. 9,10 The LA volume was also strongly associated with the prognosis of patients with acute myocardial infarction 11 and dilated cardiomyopathy. 12 Methods to calculate LA volume have been described, [3][4][5][6] but the distribution of LA volume in normal Japanese subjects who do not have cardiovascular disease has not been reported. Our objective was to provide reference ranges of the LA volume in healthy Japanese adults. Methods Study SubjectsEligible subjects were adults ≥20 years of age who were referred for outpatient transthoracic echocardiographic examination because of non-specific chest symptoms. All subjects had sinus rhythm, and no history of atrial arrhyth-

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“…20 The left atrial phasic volumes were calculated by the modified Simpson's method from the apical four chamber view at the onset of P-wave on the ECG [pre-atrial contraction volume, V p ( Figure 1 . [21][22][23] These values were corrected for the body surface area (BSA). For the assessment of LA mechanical functions, the following indices calculated from the volumes were used.…”

Section: Echocardiographymentioning

confidence: 99%

“…2,28 Immediately after the BMV procedure a repeat echocardiogram was performed to define the success of procedure as mentioned previously. 15,[16][17][18][19][20][21][22][23][24][25][26][27][28][29] All patients, in whom BMV was successful, underwent a repeat echocardiographic evaluation 24-48 hours after the procedure for the measurement of post-procedural parameters.…”

Section: Echocardiographymentioning

confidence: 99%

Acute Impact of Balloon Mitral Valvotomy on Left Atrial Functions in Mitral Stenosis

Beig¹,

Dar²,

Kumar³

et al. 2017

JCDR

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Background: Rheumatic mitral stenosis (MS) is associated with progressive impairment of left atrial (LA) mechanical functions. This study was conducted to assess the acute impact of Balloon Mitral Valvotomy (BMV) on these functions. Methods: This single centre observational study included 25 patients with severe MS (aged 34.1 ± 7.1 years, with mean mitral valve area of 0.74 ± 0.13 cm²), in sinus rhythm, who underwent successful BMV at our hospital. Phasic LA volumes (V max : maximal LA volume, V min : minimal LA volume, and V p : LA volume at the onset of P-wave) were measured by modified Simpson's method. Parameters of LA reservoir function i.e. LA total emptying fraction (LATEF) and LA expansion index (LAEI); conduit function i.e. LA passive emptying fraction (LAPEF); and pump function i.e. LA active emptying fraction (LAAEF) were calculated from these volumes. All these parameters were evaluated before and 24-48 hours after BMV. Results: Successful BMV led to significant reduction in V max (p < 0.001), V min (p < 0.001), and V p (p < 0.001). There was a significant increase in LATEF (p= 0.001) and LAEI (p= 0.002). LAPEF increased insignificantly (p= 0.057), while there was no significant change in LAAEF (p =0.127) after BMV. Conclusion: Successful BMV leads to early improvement in left atrial reservoir and conduit functions, without significantly affecting left atrial pump function. Whether these acute changes translate into long term left atrial reverse remodelling and clinical benefits thereof needs to be established by further studies.

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Normal left atrial function determined by 2-dimensional echocardiography

Cited by 135 publications

References 28 publications

Effect of Cardiac Resynchronization Therapy on Left Atrial Reverse Remodeling and Spontaneous Echo Contrast

Effect of Cardiac Resynchronization Therapy on Left Atrial Reverse Remodeling and Spontaneous Echo Contrast

Left Atrial Volume in Normal Japanese Adults

Acute Impact of Balloon Mitral Valvotomy on Left Atrial Functions in Mitral Stenosis

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