Normal Flora and Acute Inflammation

Intestinal, segmented, filamentous bacteria

“…It is only known that some components of the autochthonous g.i. microbiota can stimulate non-specific immunity, either systemically [59,[79][80][81][82] or locally [18,[81][82][83][84][85][86][87][88] or both systemically and locally [82,89,90]. Autochthonous gut bacteria can also stimulate specific immunity [91][92][93][94][95] anO induce specific immunological tolerance [60,92,94,[96][97][98].…”

Fungal endocarditis: patients at risk and their treatment

“…directly by antibiotics (Seelig, 1966a, b), or by suppression of enteric flora as in gnotobiotic animals (Abrams and Bishop, 1965). Major surgery, and other serious trauma, e.g.…”

Leukocytic Mechanisms in Inflammation

“…When sterile starch-tryptose is injected intraperitoneaIIy, the exuda tion of fluid and protein is the same in normal and germ-free mice (288). The exudation of leukocytes is diminished in the latter (288,289) although the sequence of cellular events is unchanged.…”