Normal echocardiographic mitral and aortic valve thickness in children

Webb, Rachel; Culliford-Semmens, Nicola; Sidhu, Karishma; Wilson, Nigel

doi:10.1136/heartasia-2016-010872

Cited by 11 publications

(9 citation statements)

References 27 publications

(18 reference statements)

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“…This is despite the fact the AMVL thickening had an objective measure (of >3 mm) while AV thickening was a subjective observation. Webb and colleagues found similarly high inter-observer agreement in relation to MV thickness measurements with an inter-class correlation coefficient of 0.85 27. They applied the same strict methodology as described in the WHF diagnostic guidelines 7…”

Section: Discussionmentioning

confidence: 83%

Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria

et al. 2019

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ObjectiveDifferent definitions have been used for screening for rheumatic heart disease (RHD). This led to the development of the 2012 evidence-based World Heart Federation (WHF) echocardiographic criteria. The objective of this study is to determine the intra-rater and inter-rater reliability and agreement in differentiating no RHD from mild RHD using the WHF echocardiographic criteria.MethodsA standard set of 200 echocardiograms was collated from prior population-based surveys and uploaded for blinded web-based reporting. Fifteen international cardiologists reported on and categorised each echocardiogram as no RHD, borderline or definite RHD. Intra-rater and inter-rater reliability was calculated using Cohen’s and Fleiss’ free-marginal multirater kappa (κ) statistics, respectively. Agreement assessment was expressed as percentages. Subanalyses assessed reproducibility and agreement parameters in detecting individual components of WHF criteria.ResultsSample size from a statistical standpoint was 3000, based on repeated reporting of the 200 studies. The inter-rater and intra-rater reliability of diagnosing definite RHD was substantial with a kappa of 0.65 and 0.69, respectively. The diagnosis of pathological mitral and aortic regurgitation was reliable and almost perfect, kappa of 0.79 and 0.86, respectively. Agreement for morphological changes of RHD was variable ranging from 0.54 to 0.93 κ.ConclusionsThe WHF echocardiographic criteria enable reproducible categorisation of echocardiograms as definite RHD versus no or borderline RHD and hence it would be a suitable tool for screening and monitoring disease progression. The study highlights the strengths and limitations of the WHF echo criteria and provides a platform for future revisions.

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Section: Discussionmentioning

confidence: 83%

Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria

et al. 2019

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“…Continuous-wave Doppler interrogation of regurgitation was performed to assess peak velocity, duration through the cardiac cycle and spectral envelope. Valve leaflet morphology and thickness was assessed in parasternal long axis (mitral and aortic) and parasternal short axis views (aortic valve) using previously described methods [25] . Images were electronically stored in DICOM format.…”

Section: Methodsmentioning

confidence: 99%

Echocardiography for latent rheumatic heart disease in first degree relatives of children with acute rheumatic fever: Implications for active case finding in family members

et al. 2021

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Background: Individuals with Acute Rheumatic Fever (ARF) often report a family history of ARF or Rheumatic Heart Disease (RHD) however the degree of familial susceptibility to RHD is poorly defined. This study aimed to determine RHD prevalence among first degree relatives of ARF patients using echocardiography. Methods: Children with ARF were recruited from Auckland, New Zealand. Parents and siblings 4years were offered echocardiography. Echocardiograms were reported according to World Heart Federation 2012 criteria. RHD prevalence in first degree relatives was compared to previously established population rates in the region. Findings: In total, 70 index cases with ARF were recruited. Echocardiography was performed in 94 parents and 132 siblings. There were 3 siblings with definite RHD and 9 with borderline RHD. There were 4 parents with definite RHD.

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“…While the difference in the behaviour of these features in normal and pathological situations is well described in the WHF Guidelines [3], other articles indicate that some criteria could be improved to reduce inter and intra observer differences. One article in particular found that there were no significant statistical differences in the measurement of the leaflet whether at the tip or the midpoint [7], a result affected by a lack of clearly defined metrics or points of measurement of the leaflet, when analysing the leaflet's thickness.…”

Section: Screening Protocolsmentioning

confidence: 99%

“…This disease starts manifesting at a young age, and it is estimated that over 400.000 annual cases in children (ages [5][6][7][8][9][10][11][12][13][14] in less developed countries, while little over 22.000 annual cases in more developed countries [2]. These numbers show how this disease's burden is mostly shouldered by less developed countries.…”

Section: Introduction 11 Motivationmentioning

confidence: 99%

“…They provide metrics for pathological aortic and mitral regurgitation, mitral leaflet thickness chordal thickness and leaflet motion. As new literature is made available, providing data that can challenge these guidelines [7], suggest new criteria [8] or indicate limitations [9], a deeper analysis of these guidelines should be performed in order to improve it and in doing so, help physicians perform the RHD diagnosis with greater accuracy.…”

Section: Introduction 11 Motivationmentioning

confidence: 99%

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Rheumatic Fever Characterization Based on indicators extracted from Echocardiograms exams

Pires

Coimbra

2019

2019 IEEE 6th Portuguese Meeting on Bioengineering (ENBENG)

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Todas as correções determinadas pelo júri, e só essas, foram efetuadas. O Presidente do Júri, Porto, ______/______/_________ I would like to thank my supervisor Prof. Miguel Coimbra for accepting to supervise my thesis, providing time and expertise and pushing me to new territories. It was a challenging experience, but very rewarding. I would like to thank Malik Sultan for his technical advice, general guidance and friendship during this entire process. None of this would be possible without my wife. Her support, patience through every step was instrumental to allow me to get to this point. She was also a great reviewer giving me nice pointers and suggestions. I'm also thankful for my family for providing me with moral support for my Master studies and my life in general. I would also like to thank the Instituto de Telecomunicações-IT for providing me with the dataset used in this thesis, allowing me to do the necessary research with it.

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Normal echocardiographic mitral and aortic valve thickness in children

Cited by 11 publications

References 27 publications

Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria

Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria

Echocardiography for latent rheumatic heart disease in first degree relatives of children with acute rheumatic fever: Implications for active case finding in family members

Rheumatic Fever Characterization Based on indicators extracted from Echocardiograms exams

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