Normal Diameter of the Ascending Aorta in Adults: The Impact of Stricter Criteria on Selection of Subjects Free of Disease

Syed, Muhammad Nabeel; Ahmad, Mirza Nubair; Hussaini, Sharmeen Fatima; Muhammad, Mustafa Noor; Pir, Syed Haris Ahmed; Khandheria, Bijoy K.; Ammar, Khawaja Afzal

doi:10.1016/s0735-1097(17)35464-5

Cited by 4 publications

(7 citation statements)

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“…Syed MN. et al (2017) [20] reported relevant and important data on the aorta: "The mean diameter of the ascending aorta (Asc Ao) in men was 2.91±0.40 cm, compared with 3.34±0.34 cm in prior studies. The mean diameter of Asc Ao in women was 2.70±0.36 cm, compared with 2.98±0.34 cm in prior studies.".…”

Section: Missing Data From Precision Engineering Microvascular and Ca...mentioning

confidence: 97%

“…Capillaries have a varying extent of basement membrane and pericyte coverage and can be continuous, fenestrated, or discontinuous. Figure reproduced from article [20] with its legend stating. Created with BioRender.com Based on data and diagram reported by Fleisher et al [4] reproduced here as (Figure 1) the diagram is a representation of the structure of the capillaries, but lacks the engineering precise measurements on diameters, length, and number of capillaries and branches with diameters measurements also.…”

Section: Missing Data From Precision Engineering Microvascular and Ca...mentioning

confidence: 99%

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Capillary ultrastructure anatomy and physiology: What is known, what is unknown or missing, what is wrong and what is new?

Ghanem¹

2022

GSC Adv. Res. Rev.

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This article summarizes what is already known about the capillary ultrastructure anatomy and physiology that includes one wrong physiological law of Starling and two misconceptions on capillaries cross section area and blood speed in its lumen. It also identifies missing data such as the number and diameters of capillaries branching from the terminal arteriole, and the speed of blood at the arterial and venous ends. It also summaries the evidence on new knowledge on capillary physiology namely the hydrodynamic of the porous orifice (G) tube built on a scale to capillary ultrastructure anatomy of pre-capillary sphincter and inter-cellular slits pores. It proves Starling’s law wrong and provide its correct replacement. The Tree Branching Law (TBL) corrects both misconceptions on capillaries cross section area being larger that the aorta and capillary blood speed is “very slow”. The TBL proves that the cross-section area of all capillaries is less than that of the aorta, and the blood speed in capillary is faster than generally received. The G tube’ magnetic field like hydrodynamics is the correct replacement for Starling’s law on the capillary-ISF transfer. This new capillary-ISF transfer allows for fast efficient function that meets cells and tissue demands at rest and during strenuous exercise.

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Section: Missing Data From Precision Engineering Microvascular and Ca...mentioning

confidence: 97%

Section: Missing Data From Precision Engineering Microvascular and Ca...mentioning

confidence: 99%

Capillary ultrastructure anatomy and physiology: What is known, what is unknown or missing, what is wrong and what is new?

Ghanem¹

2022

GSC Adv. Res. Rev.

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“…Normal aortic diameters vary widely and are strongly influenced by several factors (e.g., gender, age etc.) [25,26]. A simplified geometry was selected as a benchmark to emulate a real-life AAA for this current parametric and methodological study.…”

Section: Geometrymentioning

confidence: 99%

“…A simplified geometry was selected as a benchmark to emulate a real-life AAA for this current parametric and methodological study. The non-affected part of the model was assumed to have a diameter of 20 mm [25][26][27]. The aortic sac was modelled asymmetrically to match representative abnormalities.…”

Section: Geometrymentioning

confidence: 99%

Fluid-Structure Interaction in Abdominal Aortic Aneurysms: Effect of Haematocrit

Stergiou

Kanaris

Mouza

et al. 2019

Fluids

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The Abdominal Aortic Aneurysm (AAA) is a local dilation of the abdominal aorta and it is a cause for serious concern because of the high mortality associated with its rupture. Consequently, the understanding of the phenomena related to the creation and the progression of an AAA is of crucial importance. In this work, the complicated interaction between the blood flow and the AAA wall is numerically examined using a fully coupled Fluid-Structure Interaction (FSI) method. The study investigates the possible link between the dynamic behavior of an AAA and the blood viscosity variations attributed to the haematocrit value, while it also incorporates the pulsatile blood flow, the non-Newtonian behavior of blood and the hyperelasticity of the arterial wall. It was found that blood viscosity has no significant effect on von Mises stress magnitude and distribution, whereas there is a close relation between the haematocrit value and the Wall Shear Stress (WSS) magnitude in AAAs. This WSS variation can possibly alter the mechanical properties of the arterial wall and increase its growth rate or even its rupture possibility. The relationship between haematocrit and dynamic behavior of an AAA can be helpful in designing a patient specific treatment.

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“…gender, age etc.) [25,26]. A simplified geometry was selected as a benchmark to emulate a real-life AAA for this current parametric and methodological study.…”

Section: Geometrymentioning

confidence: 99%

Fluid-Structure Interaction in Abdominal Aortic Aneurysms: Effect of Haematocrit

Stergiou¹,

Kanaris²,

Mouza³

et al. 2018

Preprint

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The Abdominal Aortic Aneurysm (AAA) is a local dilation of the abdominal aorta and it is a cause for serious concern because of the high mortality associated with its rupture. Consequently, the understanding of the phenomena related to the creation and the progression of an AAA is of crucial importance. In this work the complicated interaction between the blood flow and the AAA wall is numerically examined using a fully coupled Fluid-Structure Interaction (FSI) method. The study investigates the possible link between the dynamic behaviour of an AAA and the blood viscosity variations attributed to the haematocrit value, while it also incorporates the pulsatile blood flow, the non-Newtonian behaviour of blood and the hyperelasticity of the arterial wall. It was found that blood viscosity has no significant effect on von Mises stress magnitude and distribution, whereas there is a close relation between the haematocrit value and the Wall Shear Stress (WSS) magnitude in AAAs. This WSS variation can possibly alter the mechanical properties of the arterial wall and increase its growth rate or even its rupture possibility. The relationship between haematocrit and dynamic behaviour of an AAA can be helpful in designing a patient specific treatment.

show abstract

Normal Diameter of the Ascending Aorta in Adults: The Impact of Stricter Criteria on Selection of Subjects Free of Disease

Cited by 4 publications

References 0 publications

Capillary ultrastructure anatomy and physiology: What is known, what is unknown or missing, what is wrong and what is new?

Capillary ultrastructure anatomy and physiology: What is known, what is unknown or missing, what is wrong and what is new?

Fluid-Structure Interaction in Abdominal Aortic Aneurysms: Effect of Haematocrit

Fluid-Structure Interaction in Abdominal Aortic Aneurysms: Effect of Haematocrit

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