Normal and Abnormal Early Pregnancy

Honemeyer, Ulrich; Kurjak, Asim; Monni, Giovanni

doi:10.5005/jp-journals-10009-1214

Cited by 3 publications

(4 citation statements)

References 87 publications

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“…While oral administration is the most common route, vaginal administration has been proposed as a more effective method (12) . The oral approach has a number of drawbacks, including lower absorption and more gastrointestinal side effects than the vaginal route (6) .…”

Section: Discussionmentioning

confidence: 99%

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Study of Oral Versus Vaginal Misoprostol in the Management of Early Pregnancy Loss

Abdou,

Ahmed,

Abd elhafez

et al. 2023

The Egyptian Journal of Hospital Medicine

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Background: Research conducted by specialists does not show that oral misoprostol is more successful than vaginal misoprostol to manage early pregnancy loss, and vice versa. Objective: To compare oral versus vaginal misoprostol for managing early pregnancy loss. Subjects and Methods: A prospective randomized controlled trial that was performed on 102 women attending to Obstetrics and Gynecology Department and diagnosed with missed abortion on ultrasound. They were divided into 2 groups. (Group A: Vaginal Misoprostol): Intravaginally into the posterior fornix, 51 patients were administered 600 μg of misoprostol soaked in normal saline solution, which was repeated three-hourly up to a maximum of two doses. Group B (Oral Misoprostol): Misoprostol 600 g was orally administered to 51 patients with a maximum of two doses, each separated by three hours. Results: All of incidence of hypotension, mean of satisfaction, and mean of successful rate were statistically significantly higher as compared with the cases in group B. incidence of side effects was statistically significantly higher in the cases of group B as compared with the cases in group A. Mean induction-expulsion interval in the cases of group A (9.5±3.3) was shorter as compared with the cases in group B (10.8±2.2) with non-statistically significant difference (p=0.078). conclusion: Misoprostol use by the vaginal route is more efficacious than oral route. Vaginal route was found to have cervical ripening effect and did not need much monitoring to become the first choice even over surgical for induction of labor.

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Section: Discussionmentioning

confidence: 99%

“…Misoprostol for the treatment of missed miscarriage does not have a universally approved dosing schedule, not even from the World Health Organization (5) . The oral route has a number of drawbacks, including lower absorption and more gastrointestinal side effects than the vaginal route (6) .…”

Section: Introductionmentioning

confidence: 99%

Study of Oral Versus Vaginal Misoprostol in the Management of Early Pregnancy Loss

Abdou,

Ahmed,

Abd elhafez

et al. 2023

The Egyptian Journal of Hospital Medicine

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“…Investigation of maternal (main uterine, arcuate, radial, and spiral) arteries, placental (umbilical, chorionic arterioles) vessels, and fetal (aorta and intracranial circulation) arteries flow patterns may help in order to diagnose abnormal implantation. [41][42][43][44][45][46][47] Uteroplacental blood flow may be different in missed abortions and nonembryonic gestational sacs than in normal pregnancies. Women with missed abortions and nonembryonic gestational sacs frequently showed a facilitated uteroplacental blood flow, as indicated by a higher number of myometrial blood vessels, higher frequency of flow in the intervillous space, and lower vascular impedance, compared with those in normal pregnancies.…”

Section: Early Pregnancy Blood Supply Assessment a N D Safety O F Ultrasoundmentioning

confidence: 99%

Early Pregnancy Scanning: Step-by-Step Overview

Antsaklis¹,

Papamichail²,

Theodora³

2018

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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Ultrasound is an essential tool for the evaluation of early pregnancy structures. The main method used during early pregnancy is transvaginal ultrasonography, in order to evaluate the course of the pregnancy during the first weeks. Although our knowledge on ultrasound has increased significantly during the last few years, still early pregnancy remains an area with not so well understood findings and structures. In this article, we will review the timeline of the first visualization of the most significant figures, which are expected to be present throughout the first trimester in a normally developing pregnancy. In addition, the suspicious and the diagnostic ultrasound findings of early pregnancy failure will be presented. We will highlight that the diagnosis of early pregnancy failure must be set by following the cutoff values which are established in order to eliminate the possibility of a false positive diagnosis and to avoid any harmful intervention in a viable pregnancy. Finally, we will denote the prognostic predictive value of evaluation of fetal heart rate and subchorionic hematomas presence in early pregnancy. Aim of this article is to review the literature regarding the diagnosis and prognosis of early pregnancies, improve clinicians' knowledge on this issue, and of course to help avoid or decrease possible misdiagnosis.

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“…It occurs in 11% of clinically recognized pregnancies and is not only associated with substantial healthcare and financial burden but non continuing pregnancy is upsetting for mother [2]. The percentage of missed abortion is increasing having diagnosed on routine ultrasound screening [3,4]. Majority of missed abortion occurs spontaneously however some pregnancies simply stop growing without any obvious symptoms, with a deferment in expulsion of conceptus [5].…”

Section: Introductionmentioning

confidence: 99%