Nontyphoid Salmonellosis in Renal Transplant Recipients: Report of Five Cases and Review of the Literature

Nontyphoidal Salmonella infection among recipients of hematopoietic SCT

“…10 NTS infection, mostly bacteremia, has been reported in recipients of heart and kidney transplants. [11][12][13] The recurrence rate in our case series was low at 5.5% compared with 35% reported in renal transplant recipients. 12 There was only one death attributable to Salmonella sepsis, suggesting that prompt empiric broad-spectrum antibiotic therapy in febrile HSCT patients is effective in averting mortality from NTS infection.…”

Severe sepsis from a Ciprofloxacin resistant salmonellosis in a kidney transplant recipient

“…cannot be clinically distinguished from those caused by other bacteria, as in both cases the classical symptoms are acute-onset fever, diarrhea and abdominal pain. 6,7 The incidence of salmonellosis in KTR is lower than 2% per year. 6,8 This clinical condition has a broad spectrum of gravity, but in immunocompetent hosts, bacteremia can be seen in less than 5 to 10%.…”

“…6,7 The incidence of salmonellosis in KTR is lower than 2% per year. 6,8 This clinical condition has a broad spectrum of gravity, but in immunocompetent hosts, bacteremia can be seen in less than 5 to 10%. Otherwise, in KTR it is rather common to find an extra-intestinal form of salmonellosis, such as meningitis, osteomyelitis, cholangitis and pneumonia (up to 35%), and bacteremia can be demonstrated in 60 to 70% of cases.…”

“…7 Overall, the duration of the infection tends to be longer in KTR, with relapse rates of 43 to 45%, and mortality rates of 5 to 6%. 6,10 A literature review with 37 cases of salmonellosis in KTR identified the species of Salmonella sp. in 35 patients, with predominance of S. typhimurium in 24 cases, S. panama in 3 cases, and S. johannesburg and S. enteritidis in 2 cases each.…”

“…is a rare form of infection that cannot be clinically differentiated from common acute enteritis, and usually responds well to fluoroquinolones. [6][7][8] In immunosuppressed patients, however, it can be more easily associated with bacteremia, and, consequently, to a much worse prognosis. [9][10][11] In this paper, we present a rare case of invasive diarrhea with severe sepsis caused by ciprofloxacin resistant Salmonella sp.…”