“…Malignancy is the commonest cause, accounting for 36% of perforations [48]. Perforation may also be iatrogenic (20%), diverticula-related (19%) and less commonly due to trauma, foreign body ingestion, faecal impaction, ischemia, inflammatory bowel disease, endometriosis, connective tissue disease, radiotherapy, drugs and spontaneous [4,6,7,10,11,49]. The site of perforation is often linked with its cause [4,8,10]; therefore, neoplastic, spontaneous, diverticular (in western countries), blunt trauma and ischemic perforations commonly occur on the left side of colon, whereas inflammatory bowel disease, diverticulitis (in eastern countries) and penetrating trauma perforations tend to be right-sided.…”