Nonsystemic vasculitic neuropathy

Rohatgi, Shalesh; Dave, Dhaval; Khan, Furqan

doi:10.4103/mjdrdypu.mjdrdypu_193_19

Cited by 2 publications

(3 citation statements)

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“…Vasculitic neuropathy is a common indication for nerve biopsy with a reported sensitivity of 54.76% and reports of a 5.1% increase in diagnostic yield when underwent with a combined muscle biopsy [17][18][19]. When underwent with a combined muscle and skin biopsy, cutaneous vasculitis was identified in 20% of suspected patients with vasculitic neuropathy [20].…”

Section: Vasculitismentioning

confidence: 99%

Neurosurgical Intervention for Nerve and Muscle Biopsies

Mohamed,

Caussat,

Mouhawasse

et al. 2024

Preprint

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(1) Background: Neurologic and musculoskeletal diseases represent a considerable portion of the underlying etiologies responsible for the widely prevalent symptoms of pain, weakens, numbness, and paresthesia. Because of the subjective and often nonspecific nature of these symptoms, different diagnostic modalities have been explored and utilized.; (2) Methods: Literature review; (3) Results: Nerve and muscle biopsy remains the gold standard for diagnosing many of the responsible neurological and musculoskeletal conditions. However, the need for invasive tissue sampling is diminishing as more investigations explore alternative diagnostic modalities. Because of this, it is important to explore the current role of neurosurgical intervention for nerve and muscle biopsies and its current relevance in the diagnostic landscape of neurological and musculoskeletal disorders. With consideration of the role of nerve and muscle biopsy, it is also important to explore innovations and emerging techniques for conducting these procedures. This review explores the indications and emerging techniques for neurological intervention for nerve and muscle biopsies; (4) Conclusions: The role of neurosurgical intervention for nerve and muscle biopsy remains relevant in diagnosing many neurological and musculoskeletal disorders. Biopsy is especially relevant as a supportive point of evidence for diagnosis in atypical cases. Additionally, emerging techniques have been explored to guide diagnostics and biopsy, conduct less invasive biopsies, and reduce risks of worsening neurologic function and other symptoms secondary to biopsy.

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Section: Vasculitismentioning

confidence: 99%

Neurosurgical Intervention for Nerve and Muscle Biopsies

Mohamed,

Caussat,

Mouhawasse

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Despite its variable importance, the many indications and clear diagnostic role make neurosurgical intervention for nerve biopsies an important aspect of the clinical decision making process. Vasculitic neuropathy is a common indication for nerve biopsy with a reported sensitivity of 54.76% and reports of a 5.1% increase in diagnostic yield when undergoing a combined muscle biopsy [17][18][19]. When undergoing a combined muscle and skin biopsy, cutaneous vasculitis was identified in 20% of suspected patients with vasculitic neuropathy [20].…”

Section: Nerve Biopsy Indicationsmentioning

confidence: 99%

“…Vasculitic neuropathy is a common indication for nerve biopsy with a reported sensitivity of 54.76% and reports of a 5.1% increase in diagnostic yield when undergoing a combined muscle biopsy [ 17 , 18 , 19 ]. When undergoing a combined muscle and skin biopsy, cutaneous vasculitis was identified in 20% of suspected patients with vasculitic neuropathy [ 20 ].…”

Section: Nerve Biopsy Indicationsmentioning

confidence: 99%

Neurosurgical Intervention for Nerve and Muscle Biopsies

Mohamed,

Caussat,

Mouhawasse

et al. 2024

Diagnostics

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(1) Background: Neurologic and musculoskeletal diseases represent a considerable portion of the underlying etiologies responsible for the widely prevalent symptoms of pain, weakness, numbness, and paresthesia. Because of the subjective and often nonspecific nature of these symptoms, different diagnostic modalities have been explored and utilized. (2) Methods: Literature review. (3) Results: Nerve and muscle biopsy remains the gold standard for diagnosing many of the responsible neurological and musculoskeletal conditions. However, the need for invasive tissue sampling is diminishing as more investigations explore alternative diagnostic modalities. Because of this, it is important to explore the current role of neurosurgical intervention for nerve and muscle biopsies and its current relevance in the diagnostic landscape of neurological and musculoskeletal disorders. With consideration of the role of nerve and muscle biopsy, it is also important to explore innovations and emerging techniques for conducting these procedures. This review explores the indications and emerging techniques for neurological intervention for nerve and muscle biopsies. (4) Conclusions: The role of neurosurgical intervention for nerve and muscle biopsy remains relevant in diagnosing many neurological and musculoskeletal disorders. Biopsy is especially relevant as a supportive point of evidence for diagnosis in atypical cases. Additionally, emerging techniques have been explored to guide diagnostics and biopsy, conduct less invasive biopsies, and reduce risks of worsening neurologic function and other symptoms secondary to biopsy.

show abstract

Nonsystemic vasculitic neuropathy

Cited by 2 publications

References 0 publications

Neurosurgical Intervention for Nerve and Muscle Biopsies

Neurosurgical Intervention for Nerve and Muscle Biopsies

Neurosurgical Intervention for Nerve and Muscle Biopsies

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