Nonsyndromic Gingival Fibromatosis: A Rare Case Report

Abstract

Hereditary gingival fibromatosis (HGF) is an uncommon gingival disease of attached gingiva, which is manifested as localized or generalized form. The HGF inheritance is transmitted through both autosomal dominant and recessive modes. Here, we are discussing a rare case report of an 8-year-old child with gingival fibromatosis in mixed dentition, which caused damage to his speech, mastication, and esthetics and led to significant change in his facial profile.The patient noticed that the gingival enlargement was simultaneous with deciduous dentition eruption and gradually covered entire dentition. Gingival enlargement covered all teeth anteriorly and posteriorly and only occlusal surfaces were visible. The enlarged tissue was resected by the external bevel gingivectomy under general anesthesia arch wise.The postoperative healing was satisfactory, uneventful, and there was significant change in patient’s esthetics. Patient has been kept on regular recall visits.How to cite this article: Gandhi M, Tandon S, Sharma M, Vijay A. Nonsyndromic Gingival Fibromatosis: A Rare Case Report. Int J Clin Pediatr Dent 2018;11(3):250-253.

Generalized hereditary gingival fibromatosis in a child: clinical, histopathological and therapeutic aspects

“…HGFs tend to occur in infancy, do not show sex predilection, 2,21 and great clinical variation in the expressivity of disease have been reported even in individuals in the same family. 2,23 The gingival growth usually begins at the time of eruption of the permanent dentition but also may develop with the eruption of the deciduous dentition, 3,7 as in our case, and rarely is present at birth. 7 Also, the presence of teeth appears to be necessary for that the development of HGF occurs because the condition usually disappears or recedes with loss of teeth.…”

“…7 Also, the presence of teeth appears to be necessary for that the development of HGF occurs because the condition usually disappears or recedes with loss of teeth. 2,3 There are no reports of HGF in edentulous patients. 3 Furthermore, the gingival growth may worsen during adolescence, suggesting a possible influence of sex hormones on the pathogenesis of the condition.…”

“…1,2 This condition can be generalized or localized, with varying degrees of severity. 3 The gingival overgrowth often delays teeth eruption and may cause severe functional and aesthetic problems 4 . Also, HGF may occur as an isolated disease or associated with several syndromes.…”

“…7 The gingivectomy is usually the most employed technique and has high efficacy. 3 The surgical approach minimizes the negative psychological effect in the patient and functional and aesthetic impairment, improving the quality of life. 3,8 However, follow-up and effective oral hygiene instructions are necessary for avoiding relapses.…”

“…3 The surgical approach minimizes the negative psychological effect in the patient and functional and aesthetic impairment, improving the quality of life. 3,8 However, follow-up and effective oral hygiene instructions are necessary for avoiding relapses. 1,3,7 Herein, we describe a rare non-syndromic case of generalized HGF in a child, including clinical and microscopical features, as well as highlighting the importance of correct diagnosis of this genetic condition.…”