Nonpharmacological treatment of epilepsy

Saxena, V. S.; Nadkarni, V V

doi:10.4103/0972-2327.85870

Cited by 29 publications

(15 citation statements)

References 14 publications

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“…These are a few of the factors that create the need and hence the pursuit for innovative compounds of plant origin with fewer redundant side effects. [11] Several reports are available regarding anticonvulsant activity of different plants and efforts for further exploration of their activity is still going on. [12] Indian traditional medicine system which offers many potential medicinal plants for epilepsy either in raw form or in the form of formulations.…”

Section: Introductionmentioning

confidence: 99%

Preliminary Screening of a Classical Ayurvedic Formulation for Anticonvulsant Activity

et al. 2016

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Background:Epilepsy is a serious and complex central nervous system disorder associated with recurrent episodes of convulsive seizures due to the imbalance between excitatory (glutamatergic) and inhibitory (GABAergic) neurotransmitters level in the brain. The available treatments are neither competent to control the seizures nor prevent progress of disease. Since ages, Herbal medicines have remained important sources of medicines in many parts of world which is evidenced through their uses in traditional systems of medicine i.e. Ayurveda, Siddha, Unani, Homeopathy and Chinese etc.Aim:A polyherbal formulation (containing Terminalia chebula Retz., Asparagus racemosus Willd., Embelia ribes Burm. F, Acorus calamus L., Tinospora cordifolia (Willd.) Miers, Convolvulus pluricaulis Choisy, Saussurea lappa C.B.Clarke, Achyranthes aspera L.) is mentioned in Ayurvedic classics Bhaiṣajya Ratnāvali. The aim of the study was to evaluate the anticonvulsant activity of the formulation in Maximum electroshock and Pentylenetetrazole induced convulsions in rats.Materials and Methods:In the present study, a polyherbal formulation was developed as directed by classical text and evaluated for the anticonvulsant activity using Maximal Electroshock Shock (MES) and Pentylenetetrazole (PTZ) induced convulsions in rats. Statistical comparison was done by one way ANOVA followed by the Tukey's multiple comparison test.Results:The obtained results showed that the PHF had a protective role on epilepsy. Treatment with PHF significantly improves antioxidant enzymes activities of superoxide dismutase (SOD) and glutathione (GSH) levels significantly as compared to controls. PHF also significantly decreased malonaldialdehyde (MDA) levels in the brain. Moreover, it also attenuated the PTZ-induced increase in the activity of GABA-T in the rat brain.Conclusion:These findings suggest that PHF might have possible efficacy in the treatment of epilepsy.

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Section: Introductionmentioning

confidence: 99%

Preliminary Screening of a Classical Ayurvedic Formulation for Anticonvulsant Activity

et al. 2016

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“…[1011] Yoga is popular, acceptable to the majority and also generally held to be useful and beneficial by the patients. Earlier evidence suggests the usefulness of meditation (Sahaj Yoga) practice in patients with epilepsy and later studies have demonstrated evidence for the use of yoga (Asanas, breathing exercises, relaxation techniques and meditation) as an adjuvant in management of epilepsy, possibly through its influence on the autonomic nervous system.…”

Section: Introductionmentioning

confidence: 99%

Yoga and epilepsy: What do patients perceive?

Naveen

Sinha

Girish

et al. 2013

Indian J Psychiatry

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Context:Benefit of yoga therapy in the management of epilepsy is emerging. However, there is no data available about the knowledge, attitude and practice (KAP) of yoga amongst people living with epilepsy (PLWE).Aims:This study was designed to explore the KAP about yoga among PLWE.Settings and Design:The study was conducted on 300 PLWE attending the neurology out-patient services of a tertiary care hospital.Methodology:Three hundred PLWE (male:female=173:127; age: 31.6±12.4 years) attending the neurology out-patient services of a neuropsychiatry hospital were administered a pre-tested KAP questionnaire.Results:About 87.4% were on regular anti-epileptic drugs and half (50.3%) on monotherapy. Use of complementary and alternative medicine by the respondents included: Ayurveda (26.7%), yoga (25.6%) and homeopathy (16.3%) or folk medicine (29.1%). Nearly 33.7% of the respondents reported that yoga is beneficial in managing epilepsy. More than half the respondents (54.8%) were willing to practice yoga. Those who practiced yoga opined that regular practice of yoga might reduce dosage of medication (62.8%), their side effects (51.3%) and frequency of seizures (54.5%). Majority of the patients were willing to practice yoga, if yoga services were offered.Conclusion:The gaps in KAP identified in this study point to the need for more systematic effort to bring about awareness of yoga in patients with epilepsy.

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“…26,27,28,29,30 All these procedures also influence hormonal and cerebral blood flow levels. 31,32,33,34 These all factors may lead to improve the cerebral function, enhance the alertness and concentration abilities especially the Shirodhara, the relaxing and anxiolytic actions for which are well established. In a study carried out on ADHD patients the Shirodhara procedure helped in decreasing the auditory and visual reaction time and increasing the attention span (when measured using an electronic vernier chronoscope).…”

Section: Managementmentioning

confidence: 99%

Management of Attention Deficit Hyperactivity Disorder (Adhd) Through Panchakarma

Bohra¹,

Sharma²,

Sharma³

2015

Int. J. Res. Ayurveda Pharm.

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Attention Deficit Hyperactivity Disorder (ADHD) is among the commonest childhood neurological disorders affecting the focusing, behaviour and activity controlling abilities. This disorder not only influence the learning abilities of the child but also has a significant impact on patient's social, professional and family life, affecting their relationships with parents and siblings, causing disruption at work because of decreased concentration abilities and less stable relationships thus crippling the self-esteem in every aspect. The prevalence of the disease is increasing and treatment options are just limited to the management of symptoms and that too not very efficient, no permanent cure is reported till date. So, there is need to expand the treatment modality. In Ayurveda, it can be correlated with various types of abnormal behaviours due to increased Vata and symptoms arising due to imbalance in the homeostasis between the components of Prajya (intellect). The relaxation and concentration improving Panchakarma therapies along with Vedic chant recitation (Music Therapy) for enhancing the concentration and focussing abilities can be proved as a promising treatment in the management of ADHD.

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Nonpharmacological treatment of epilepsy

Cited by 29 publications

References 14 publications

Preliminary Screening of a Classical Ayurvedic Formulation for Anticonvulsant Activity

Preliminary Screening of a Classical Ayurvedic Formulation for Anticonvulsant Activity

Yoga and epilepsy: What do patients perceive?

Management of Attention Deficit Hyperactivity Disorder (Adhd) Through Panchakarma

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