“…demonstrate the concept. Several modules were already developed, namely: (1) two modules for the electric supply of the implant: motion-driven power generators and an energy conditioning system [35][36][37][38][39]; (2) two modules for the communication between the implant and external mechanisms: a dual-link telemetry system and an activation circuit [40]; (3) a module for the detection of aseptic loosening of prosthetic stem and cup [41]; and (4) a module for the active therapeutic actuation against loosening: a mechanical stimulator of bone cells, based on six polyvinylidene fluoride actuators, to induce bone formation surrounding the implant [42].…”