Nonlinear Microfluidics

Stoecklein, Daniel; Carlo, Dino Di

doi:10.1021/acs.analchem.8b05042

Cited by 157 publications

(150 citation statements)

References 164 publications

Supporting

Mentioning

147

Contrasting

Order By: Relevance

“…These data and theoretical calculations are used to calculate the forward and transverse slip velocities from Eqs. (3)- (5). The results are shown in Fig.4(b), and we again observe that theoretical and simulation data nearly coincide.…”

Section: Resultssupporting

confidence: 66%

Inertial migration of neutrally buoyant particles in superhydrophobic channels

et al. 2020

View full text Add to dashboard Cite

At finite Reynolds numbers particles migrate across flow streamlines to their equilibrium positions in microchannels. Such a migration is attributed to an inertial lift force, and it is well-known that the equilibrium location of neutrally-buoyant particles is determined only by their size and the channel Reynolds number. Here we demonstrate that the decoration of a bottom wall of the channel by superhydrophobic grooves provides additional possibilities for manipulation of neutrally-buoyant particles. It is shown that the effective anisotropic hydrodynamic slip of such a bottom wall can be readily used to alter the equilibrium positions of particles and to generate their motion transverse to the pressure gradient. These results may guide the design of novel inertial microfluidic devices for efficient sorting of neutrally-buoyant microparticles by their size.

show abstract

Section: Resultssupporting

confidence: 66%

Inertial migration of neutrally buoyant particles in superhydrophobic channels

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Next, we discuss the forces acting on the particle to explain its migration dynamics. In the case of a neutrally buoyant rigid particle suspended in a Newtonian fluid, the particle migration and final equilibrium position are determined by two opposing forces acting on the particle: these forces are the wall induced lift force that pushes the particle away from the wall and the shear-gradient induced lift force that drives the particle towards the wall, the latter resulting from the rigid particle resistance to deformation [28,64]. When the particle is deformable, its dynamics is further complicated by the additional force originating from the particle shape deformation, which depends on the elastic properties of the material (e.g., the elastic modulus G) [30,31].…”

Section: Resultsmentioning

confidence: 99%

“…This is the case for typical inertial microfuidics applications (Re > 1 and W e > 0), when inertial and elastic forces dominate the cross-streamline migration and final equilibrium position of the particles. In particular, elasto-inertial microfluidics is emerging as a powerful tool and research area, with devices where elasticity and inertia are being engineered to achieve efficient particle focusing and/or particle sorting [16].…”

Section: Introductionmentioning

confidence: 99%

Inertial migration of a deformable particle in pipe flow

2019

View full text Add to dashboard Cite

We perform fully Eulerian numerical simulations of an initially spherical hyperelastic particle suspended in a Newtonian pressure-driven flow in a cylindrical straight pipe. We study the full particle migration and deformation for different Reynolds numbers and for various levels of particle elasticity, to disentangle the interplay of inertia and elasticity on the particle focusing. We observe that the particle deforms and undergoes a lateral displacement while traveling downstream through the pipe, finally focusing at the pipe centerline. We note that the migration dynamics and the final equilibrium position are almost independent of the Reynolds number, while they strongly depend on the particle elasticity; in particular, the migration is faster as the elasticity increases (i.e. the particle is more deformable), with the particle reaching the final equilibrium position at the centerline in shorter times. Our simulations show that the results are not affected by the particle initial conditions, position and velocity. Finally, we explain the particle migration by computing the total force acting on the particle and its different components, viscous and elastic.

show abstract

“…A larger value of

W i

indicates a stronger elasticity effect, which may be a result of either an extended relaxation time or an increased fluid velocity. The inertial effect is characterized by the Reynolds number ,

R e = \frac{2 ρ V w h}{η (w + h)}

where ρ is the fluid density, h is the microchannel height, and η is the fluid viscosity. The Reynolds number is on the order of 0.01 in the majority of our tests.…”

Section: Methodsmentioning

confidence: 99%

Elastic instabilities in the electroosmotic flow of non‐Newtonian fluids through T‐shaped microchannels

Song

et al. 2019

Electrophoresis

View full text Add to dashboard Cite

Elastic instabilities in the electroosmotic flow of non-Newtonian fluids through T-shaped microchannelsElectroosmotic flow (EOF) has been widely used to transport fluids and samples in microand nanofluidic channels for lab-on-a-chip applications. This essentially surface-driven plug-like flow is, however, sensitive to both the fluid and wall properties, of which any inhomogeneity may draw disturbances to the flow and even instabilities. Existing studies on EOF instabilities have been focused primarily upon Newtonian fluids though many of the chemical and biological solutions are actually non-Newtonian. We carry out a systematic experimental investigation of the fluid rheological effects on the elastic instability in the EOF of phosphate buffer-based polymer solutions through T-shaped microchannels. We find that electro-elastic instabilities can be induced in shear thinning polyacrylamide (PAA) and xanthan gum (XG) solutions if the applied direct current voltage is above a threshold value. However, no instabilities are observed in Newtonian or weakly shear thinning viscoelastic fluids including polyethylene oxide (PEO), polyvinylpyrrolidone (PVP), and hyaluronic acid (HA) solutions. We also perform a quantitative analysis of the wave parameters for the observed elasto-elastic instabilities.

show abstract

Nonlinear Microfluidics

Cited by 157 publications

References 164 publications

Inertial migration of neutrally buoyant particles in superhydrophobic channels

Inertial migration of neutrally buoyant particles in superhydrophobic channels

Inertial migration of a deformable particle in pipe flow

Elastic instabilities in the electroosmotic flow of non‐Newtonian fluids through T‐shaped microchannels

Contact Info

Product

Resources

About