“…The method has also been used to explore the relative contributions of the optical and neural systems to the reduced resolution found in the retinal periphery (Green, 1970a;Enoch and Hope, 1973;Frisen and Glansholm, 1975), the optical and neural changes with age (Morrison and McGrath, 1985), the visibility of isoluminant gratings and the sampling density of neurons that mediate colour vision (Sekiguchi et al, 1993a,b) and non-linearities in the visual system (Burton, 1973;Macleod etal., 1992). Observation of aliasing effects between the fringes and the retinal mosaic in the central and peripheral retina has given valuable new information on spatial arrangement of the retinal receptors (Williams 1985(Williams , 1988(Williams , 1992Thibos etal., 1987a, b;Sekiguchi et al, 1991;Anderson et al, 1992). A further area of basic investigation has been the oblique effect and meridional amblyopia, where the use of the fringes has convincingly demonstrated that the origins of these phenomena lie in the retina and or the higher visual pathways (Campbell etal., 1966;Mitchell etal., 1967Mitchell etal., , 1969, rather than in residual uncorrected optical errors.…”