2023
DOI: 10.22541/au.167938961.12926545/v1
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Nonlinear Control of a Hybrid Pneumo-Hydraulic Mock Circuit of the Cardiovascular System

Abstract: Objective: Hybrid cardiovascular mock circuits (HMC), designed for dynamic testing of Ventricular Assist Devices (VAD), offer physiologic accuracy by sequestering model complexity in silico and ease of construction by reducing number of model elements in vitro. Despite superior response time and precision, pneumatic actuation is avoided in HMCs due to nonlinear dynamics and noise. We tested the hypothesis that a HMC consisting of a variable elastance-driven numerical circuit coupled to a pneumo-hydraulic physi… Show more

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