Nonlinear analysis of the EEG of schizophrenics with optimal embedding dimension

Jeong, Jaeseung; Kim, Daijin; Chae, Jeong‐Ho; Kim, Soo Yong; Ko, Hyojin; Paik, In‐Ho

doi:10.1016/s1350-4533(98)00078-2

Cited by 82 publications

(53 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although there was no significant correlation between LZC and medication dosageequivalents, drug effects cannot be ruled out. Previously, Jeong et al (1998) and Kim et al (2000) likewise found no correlation between antipsychotic dose and complexity values. Nevertheless, authors were cautious when interpreting this absence of significant correlations.…”

Section: Significancementioning

confidence: 83%

“…as measured using electroencephalography (EEC) or magnetoencephalography (MEG). EEG-MEG complexity analyses usually measure the regularity/predictability of brain oscillations and/or attempt to estimate the number of independent oscillators underlying the observed signal (Lutzenberger et al, 1995;Jeong et al, 1998). Numerous complexity measures have been proposed (see Tononi et al, 1998) including: dimensional complexity, algorithmic complexity, neural complexity, fractal dimension, first Lyapunov component, correlation dimension, Lempel-Ziv Complexity (LZC), etc.…”

Section: Introductionmentioning

confidence: 99%

“…Numerous complexity measures have been proposed (see Tononi et al, 1998) including: dimensional complexity, algorithmic complexity, neural complexity, fractal dimension, first Lyapunov component, correlation dimension, Lempel-Ziv Complexity (LZC), etc. (Elbert et al, 1992;Koukkou et al, 1993;Jeong et al, 1998;Kim et al, 2000;Kotini and Anninos, 2002;Li et al, 2008). For example, the dimensional complexity refers to the classical method of the so-called correlation dimension.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Lempel–Ziv complexity in schizophrenia: A MEG study

Fernández

López‐Ibor

Turrero

et al. 2011

Clinical Neurophysiology

View full text Add to dashboard Cite

SchizophreniaLempel-Ziv complexity Magnetoencephalography Neurodevelopmental Neurodegenerative• Schizophrenic patients show higher complexity values as compared to controls.• Schizophrenic patients showed a tendency to reduced complexity values as a function of age while controls showed the opposite tendency.• The tendency observed in schizophrenic patients parallels the tendency observed in Alzheimer disease patients. ABSTRACTObjective: The neurodevelopmental-neurodegenerative debate is a basic issue in the field of the neuropathological basis of schizophrenia (SCH). Neurophysiological techniques have been scarcely involved in such debate, but nonlinear analysis methods may contribute to it. Methods: Fifteen patients (age range 23-42 years) matching DSM IV-TR criteria for SCH, and 15 sex-and age-matched control subjects (age range 23-42 years) underwent a resting-state magnetoencephalographic evaluation and Lempel-Ziv complexity (LZC) scores were calculated. Results: Regression analyses indicated that LZC values were strongly dependent on age. Complexity scores increased as a function of age in controls, while SCH patients exhibited a progressive reduction of LZC values. A logistic model including LZC scores, age and the interaction of both variables allowed the classification of patients and controls with high sensitivity and specificity. Conclusions: Results demonstrated that SCH patients failed to follow the "normal" process of complexity increase as a function of age. In addition, SCH patients exhibited a significant reduction of complexity scores as a function of age, thus paralleling the pattern observed in neurodegenerative diseases. Significance: Our results support the notion of a progressive defect in SCH, which does not contradict the existence of a basic neurodevelopmental alteration.

show abstract

Section: Significancementioning

confidence: 83%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Lempel–Ziv complexity in schizophrenia: A MEG study

Fernández

López‐Ibor

Turrero

et al. 2011

Clinical Neurophysiology

View full text Add to dashboard Cite

show abstract

“…Correlation dimension has been successfully used in detecting relative changes in EEG obtained from Schizophrenic patients [8], Alzheimer's patient [9], Alcohol Users [10]. Embedding dimension, which is derived using correlation dimension, helps construct the arrangement of neural signals spatially recorded using EEG.…”

Section: Introductionmentioning

confidence: 99%

“…Embedding dimension, which is derived using correlation dimension, helps construct the arrangement of neural signals spatially recorded using EEG. It has been used to explore the brain mechanism in Schizophrenia [8] and epilepsy [11]. Cultural acceptance of alcohol or its traditional use in ritual influences ones consumption pattern.…”

Section: Introductionmentioning

confidence: 99%