Noninvasive versus invasive ventilation for acute respiratory failure in patients with hematologic malignancies: A 5-year multicenter observational survey*

Gristina, Giuseppe R.; Antonelli, Massimo; Conti, Giorgio; Ciarlone, Alessia; Rogante, S; Rossi, Carlotta; Bertolini, Guido

doi:10.1097/ccm.0b013e3182227a27

Cited by 186 publications

(121 citation statements)

References 35 publications

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“…[60][61][62]. A large observational multicentre Italian survey investigated the clinical impact of NIV use in 1302 haematological patients admitted to the ICU with ARF [63]. The authors, after a propensity score analysis, confirmed the role of NIV as an independent predictor of survival.…”

Section: Recommendationmentioning

confidence: 73%

Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure

et al. 2017

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Section: Recommendationmentioning

confidence: 73%

Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure

et al. 2017

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“…Most observational studies and subgroup analyses of RCT show that patients with acute respiratory distress syndrome (ARDS) are among those with the worst outcome when they receive NIV as a support measure for severe hypoxemic ARF, with high rates of NIV failure (28,30,(35)(36)(37)(38), and limited efficacy of NIV. The severity of arterial hypoxemia and the frequent impairment of pulmonary mechanics in these patients may explain the high intubation rate showed in several studies, regardless of NIV use or not.…”

Section: Acute Respiratory Distress Syndromementioning

confidence: 99%

The art and science of non-invasive ventilation

Ferrer¹

2014

sob

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SummaryNon-invasive ventilation (NIV) is one of the most relevant recent advances in the management of patients with severe acute respiratory failure (ARF). NIV is considered a standard of care for the management of hypercapnic ARF in patients with acute exacerbation of chronic obstructive pulmonary disease. With an appropriate selection of patients, NIV can reduce the need for invasive mechanical ventilation, mortality and length of stay. Patients with severe hypoxemic ARF have in general a lower likelihood to need tracheal intubation when NIV as a support for ARF is added to the standard medical treatment. However, the effects of NIV on mortality are less evident, and the heterogeneity of the different published studies suggests that the efficacy may be different among different populations. The optimal time for intubation after NIV failure remains a challenging issue due to increasing evidences on the relationship between delayed intubation and excess mortality in these populations. In intubated patients with preexisting lung disease, the use of NIV in order to advance extubation during difficult and prolonged weaning can result in reduced periods of endotracheal intubation, complication rates and improved survival. Moreover, NIV immediately after extubation is effective in avoiding respiratory failure after extubation and improving survival in patients at risk for this complication, particularly those with chronic respiratory disorders, cardiac co-morbidity, and hypercapnic respiratory failure.KEY WORDS: non-invasive ventilation, acute respiratory failure, weaning, hypoxemic respiratory failure, hypercapnic respiratory failure. IntroductionNon-invasive ventilation (NIV) is one of the most relevant recent advances in the management of patients with severe acute respiratory failure (ARF). Non-invasive ventilation is ventilatory support through the upper airways of patients with an interface, usually a mask; therefore, tracheal intubation or a tracheostomy is not needed. The benefits of NIV appear to be the consequence of avoiding tracheal intubation and the associated morbidity and mortality (1, 2). There are several potential advantages for the use of NIV. Some patients can be managed out of an intensive care unit (ICU), a particularly stressful environment, with additional benefits in reducing the occupation of ICU beds and related costs. Ventilatory support can be intermittent and therefore withdrawal of NIV can be gradual. These patients can cooperate in respiratory therapy; they can receive nebulised therapy, expectorate and communicate with staff and their relatives. However, there are limitations for NIV. Unnecessary delay in intubation of those patients who fail with NIV treatment is associated with worse outcome (3). Some patients do not tolerate the mask due to claustrophobia or other causes, and nasal bridge skin breakdown can occur and difficult the use of NIV. Non-invasive ventilation is now considered as a firstline intervention in selected patients with severe exacerbation of chronic obstructive...

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“…4.478 cies who are admitted to an intensive care unit (ICU) for respiratory support, half will require mechanical ventilation [9]. However, the need for mechanical ventilation in patients with hematologic malignancies is associated with a poor prognosis [10,11].…”

Section: Introductionmentioning

confidence: 99%

Clinical Outcomes of Extracorporeal Membrane Oxygenation Support for Patients With Hematologic Malignancies

Kang

Lim²,

Lee³

et al. 2014

Chest

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Noninvasive versus invasive ventilation for acute respiratory failure in patients with hematologic malignancies: A 5-year multicenter observational survey*

Cited by 186 publications

References 35 publications

Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure

Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure

The art and science of non-invasive ventilation

Clinical Outcomes of Extracorporeal Membrane Oxygenation Support for Patients With Hematologic Malignancies

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