Noninvasive ventilation for weaning in hypoxemic respiratory failure: not ready for prime time

Laghi, Franco; Fernández, Rafael

doi:10.1007/s00134-012-2680-3

Cited by 4 publications

(3 citation statements)

References 9 publications

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“…The authors concluded that, in a highly experienced centre, early extubation followed by NIV is feasible and might facilitate liberation from mechanical ventilation in selected patients with hypoxaemic ARF. These findings were discussed in the editorial by Laghi and Fernandez [4]. …”

Section: Noninvasive Ventilationmentioning

confidence: 93%

Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient–ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea

et al. 2013

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Section: Noninvasive Ventilationmentioning

confidence: 93%

Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient–ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea

et al. 2013

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“…Up to now, there are few available bedside measurements for prediction of NIV outcome and the decision to discontinue NIV is mainly based on clinical and physiologic parameters [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

“…Indeed, although sophisticated methods have been proposed to predict weaning outcome [ 8 ], none of these methods has ever achieved a wide bedside use because of their invasiveness, of the inconsistent results, and of the need for trainee personnel and complicated equipment. Consequently, the rapid shallow breathing index is still preferable to these methods because of its simpler application and more immediate interpretation [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Diaphragm thickening fraction predicts noninvasive ventilation outcome: a preliminary physiological study

et al. 2021

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Background A correlation between unsuccessful noninvasive ventilation (NIV) and poor outcome has been suggested in de-novo Acute Respiratory Failure (ARF) patients. Consequently, it is of paramount importance to identify accurate predictors of NIV outcome. The aim of our preliminary study is to evaluate the Diaphragmatic Thickening Fraction (DTF) and the respiratory rate/DTF ratio as predictors of NIV outcome in de-novo ARF patients. Methods Over 36 months, we studied patients admitted to the emergency department with a diagnosis of de-novo ARF and requiring NIV treatment. DTF and respiratory rate/DTF ratio were measured by 2 trained operators at baseline, at 1, 4, 12, 24, 48, 72 and 96 h of NIV treatment and/or until NIV discontinuation or intubation. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the ability of DTF and respiratory rate/DTF ratio to distinguish between patients who were successfully weaned and those who failed. Results Eighteen patients were included. We found overall good repeatability of DTF assessment, with Intra-class Correlation Coefficient (ICC) of 0.82 (95% confidence interval 0.72–0.88). The cut-off values of DTF for prediction of NIV failure were < 36.3% and < 37.1% for the operator 1 and 2 (p < 0.0001), respectively. The cut-off value of respiratory rate/DTF ratio for prediction of NIV failure was > 0.6 for both operators (p < 0.0001). Conclusion DTF and respiratory rate/DTF ratio may both represent valid, feasible and noninvasive tools to predict NIV outcome in patients with de-novo ARF. Trial registration ClinicalTrials.gov Identifier: NCT02976233, registered 26 November 2016.

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Noninvasive ventilation in blunt chest trauma: beware of missed esophageal injuries!

et al. 2014

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Noninvasive ventilation for weaning in hypoxemic respiratory failure: not ready for prime time

Cited by 4 publications

References 9 publications

Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient–ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea

Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient–ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea

Diaphragm thickening fraction predicts noninvasive ventilation outcome: a preliminary physiological study

Noninvasive ventilation in blunt chest trauma: beware of missed esophageal injuries!

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