Noninvasive Ventilation and Spinal Cord Injury

Daoud, Azhar S.; Haider, Samran; Sankari, Abdulghani

doi:10.1016/j.jsmc.2020.08.006

Cited by 12 publications

(3 citation statements)

References 54 publications

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“…Veterans with spinal cord injuries and disorders (SCI/D) commonly experience impairments in physiological function, activities of daily living, and long‐term health (Sankari et al., 2019 ). Since respiratory impairment following SCI/D is typically more profound in the supine position (Sankari et al., 2014 ), positive airway pressure (PAP) therapy is often recommended (Daoud et al., 2020 ). However, adherence to PAP therapy remains a challenge despite education, follow‐up, and support (Sawyer et al., 2011 ).…”

Section: Introductionmentioning

confidence: 99%

Feasibility of oropharyngeal and respiratory muscle training in individuals with OSA and spinal cord injury or disease: A pilot study

Sankari,

Najjar,

Maresh

et al. 2024

Physiological Reports

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ObjectivesTo examine the feasibility of individuals with spinal cord injury or disease (SCI/D) to perform combined oropharyngeal and respiratory muscle training (RMT) and determine its impact on their respiratory function.MethodsA prospective study at a single Veterans Affairs (VA) Medical Center. Inclusion criteria included: 1) Veterans with chronic SCI/D (>6 months postinjury and American Spinal Injury Association (ASIA) classification A–D) and 2) evidence of OSA by apnea‐hypopnea index (AHI ≥5 events/h). Eligible participants were randomly assigned to either an experimental (exercise) group that involved performing daily inspiratory, expiratory (using POWERbreathe and Expiratory Muscle Strength Trainer 150 devices, respectively), and tongue strengthening exercises or a control (sham) group that involved using a sham device, for a 3‐month period. Spirometry, maximal expiratory pressure (MEP), maximal inspiratory pressure (MIP), polysomnography, and sleep questionnaires were assessed at baseline and at 3 months.ResultsTwenty‐four individuals were randomized (12 participants in each arm). A total of eight (67%) participants completed the exercise arm, and ten (83%) participants completed the sham arm. MIP was significantly increased (p < 0.05) in the exercise group compared with the baseline.ConclusionsCombined oropharyngeal and RMT are feasible for individuals with SCI/D. Future studies are needed to determine the clinical efficacy of these respiratory muscle exercises.

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Section: Introductionmentioning

confidence: 99%

Feasibility of oropharyngeal and respiratory muscle training in individuals with OSA and spinal cord injury or disease: A pilot study

Sankari,

Najjar,

Maresh

et al. 2024

Physiological Reports

Self Cite

View full text Add to dashboard Cite

show abstract

“…It is estimated that there are approximately 282,000 people in the United States living with spinal cord injury (SCI), with 17,000 new cases each year (National Spinal Cord Injury Statistical Center, 2016). Respiratory dysfunction is a major cause of morbidity and mortality in people with SCI, particularly in cervical injury levels (Daoud et al, 2020). Individuals with cervical SCI experience chronic intermittent hypoxia (CIH) secondary to multiple factors, including abnormal chest wall mechanics, decreased lung volume, impaired respiratory muscles, and disordered breathing during sleep (Bascom et al, 2015; Brown et al, 2006; Daoud et al, 2020; Sankari, Bascom, Chowdhuri, et al, 2014; Sankari, Bascom, Oomman, et al, 2014; Sankari, Martin, et al, 2015; Scanlon et al, 1989).…”

Section: Introductionmentioning

confidence: 99%

“…Respiratory dysfunction is a major cause of morbidity and mortality in people with SCI, particularly in cervical injury levels (Daoud et al, 2020). Individuals with cervical SCI experience chronic intermittent hypoxia (CIH) secondary to multiple factors, including abnormal chest wall mechanics, decreased lung volume, impaired respiratory muscles, and disordered breathing during sleep (Bascom et al, 2015; Brown et al, 2006; Daoud et al, 2020; Sankari, Bascom, Chowdhuri, et al, 2014; Sankari, Bascom, Oomman, et al, 2014; Sankari, Martin, et al, 2015; Scanlon et al, 1989). Conversely, respiratory plasticity in response to CIH may contribute to respiratory recovery following cervical SCI (Ling et al, 2001).…”

Section: Introductionmentioning

confidence: 99%