Noninvasive ventilation acutely modifies heart rate variability in chronic obstructive pulmonary disease patients

Abstract

Sympathetic and parasympathetic neural control of heart rate is altered in COPD patients and that BiPAP acutely improves ventilation, enhances sympathetic response and decreases vagal tonus. The improvement of ventilation caused by BiPAP was associated with reduced cardiac vagal activity in stable moderate-to-severe COPD patients.

Evidence for Autonomic Function and Its Influencing Factors in Subjects With COPD: A Systematic Review

“…4,11,27,32,36,38,40 Still, in other studies, medication use was completely avoided for a period of 6 -24 h before autonomic function assessment. 17,29,34,39 Nevertheless, these variations in medication use are not likely to affect our results because none of the studies included medications that could have had any significant effect on the autonomic nervous system. We also noticed differences in heart rate variability assessment procedures across the studies.…”

“…37 However, 3 studies reported comparable time-domain parameters between subjects with COPD and healthy controls. 36,39,41 The frequency-domain values for heart rate variability showed more variation across the studies. Lower frequencydomain values were reported in some studies for LF, 3 10,34,38,44 and HFnu in subjects with COPD compared with their healthy counterparts.…”

“…Fifteen studies of high methodological quality investigated the differences in heart rate variability values between subjects with COPD and healthy controls. 3,10,13,19,[34][35][36][37][38][39][40][41][42][43][44] Most of these studies reported significantly lower heart rate variability in subjects with COPD. Specifically, the time-domain parameters in most of the studies (12 of 15) showed that subjects with COPD had lower heart rate variability compared with healthy controls.…”

Controle autonômico da frequência cardíaca de pacientes com doenças cardiorrespiratórias crônicas e indivíduos saudáveis em repouso e durante a manobra de acentuação da arritmia sinusal respiratória

“…By observing the indices of the time domain, some authors found that these individuals have a reduced heart rate variability (HRV), however the values of spectral analysis showed a predominance of vagal action (reflecting the vagal hyperactivity observed in the airway) [5][6][7][8] . Other authors 9,10 found an increase in sympathetic activity in HR control, although they agree that there is a reduction in HRV in patients with COPD.…”

Efeito da técnica de oscilação oral de alta freqüência aplicada em diferentes pressões expiratórias sobre a função autonômica do coração e os parâmetros cardiorrespiratórios

“…Um meio de avaliar o comportamento autonômico é pela análi-se da variabilidade da freqüência cardíaca (VFC), um método simples e não-invasivo que pode ser utilizado para identificar fenômenos relacionados ao SNA 7 tanto em indivíduos saudáveis 8,9 quanto em portadores de doença 10,11 . Esse método também tem sido utilizado na avaliação da função autonômica durante a aplicação de exercícios respiratórios 12 e outras técnicas da fisioterapia respiratória 13,14 .…”