Noninvasive serum N-glycans associated with ovarian cancer diagnosis and precancerous lesion prediction
Si Liu,
Chang Tu,
Haobo Zhang
et al.
Abstract:Background
Ovarian cancer (OC) is one of the most common gynecological tumors with high morbidity and mortality. Altered serum N-glycome has been observed in many diseases, while the association between serum protein N-glycosylation and OC progression remains unclear, particularly for the onset of carcinogenesis from benign neoplasms to cancer.
Methods
Herein, a mass spectrometry based high-throughput technique was applied to characterize serum N-g… Show more
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