Noninvasive Prediction of Renal Stone Surface Irregularities by Numerical Analysis of the Color Doppler Twinkling Artifact: An Ex Vivo Study

Jamzad, Amoon; Setarehdan, Seyed Kamaledin

doi:10.1002/jum.14465

Cited by 3 publications

(2 citation statements)

References 46 publications

(97 reference statements)

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“…В качестве причин ложноположительных случаев выявления АМ отмечены нефрокальциноз и кальцификация сосудов [63]. Ряд ра-бот основан на попытке учитывать интенсивность АМ для предположения о структуре конкремента и его химическом составе [67][68][69][70].…”

Section: определение возможностей использования артефакта мерцания дл...unclassified

Doppler twinkling artifact: physical mechanisms and place in diagnostic practice. State of the art

Громов

Sapozhnikov²,

Каприн

2022

Medicinskaâ vizualizaciâ

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The twinkling artifact has been known to specialists in ultrasound diagnostics since 1996. However, until now there is no understanding of the reasons for its appearance, and the place of its application in diagnostics.Material and methods. Electronic databases (PubMed, E-library, Web of Science) were searched studies using the keyword – “twinkling artifact”. The scientific publications on the Doppler twinkling artifact from the moment of the first reports about its existence is systematized and analyzed. The authors' own developments on this topic are presented. Modern views on this phenomenon and its place in ultrasound diagnostics are described. An explanation of the physical mechanisms of this phenomenon is given.Results. Recommendations are formulated for practitioners on changing the settings of an ultrasound scanner in order to increase twinkling artifact detectability. The directions of using the artifact to obtain additional diagnostic signs of pathological changes, which currently include the diagnosis of nephro-, uretero- and choledocholithiasis, are determined.Conclusions. The high efficiency of the use of the twinkling artifact for the diagnosis of small kidney stones, comparable with the capabilities of computed tomography, has been shown.

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Section: определение возможностей использования артефакта мерцания дл...unclassified

Doppler twinkling artifact: physical mechanisms and place in diagnostic practice. State of the art

Громов

Sapozhnikov²,

Каприн

2022

Medicinskaâ vizualizaciâ

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“…Currently, there are no standards for optimizing ultrasound twinkling parameters or quantifying the twinkling signature in the clinical setting, and this is mainly because the mechanistic causes of ultrasound twinkling remain elusive. Surface roughness or irregularities and internal porosity of complicated objects have been described as contributors to the twinkling signature hypothesized to reflect phase-shift phenomena that arise in ultrasound wave propagation, interactions with bubbles or during cavitation [3][4][5][6][7][8]. In recent years, using fiducials detectable by ultrasound twinkling [9,10] has gained some translation into the clinical setting despite not fully understanding the physics of twinkling or how to optimize the scanning parameters for generating twinkling.…”

Section: Introductionmentioning

confidence: 99%

Twinkling-guided ultrasound detection of polymethyl methacrylate as a potential breast biopsy marker: a comparative investigation

et al. 2022

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Since its first description 25 years ago, color Doppler twinkling has been a compelling ultrasound feature in diagnosing urinary stones. While the fundamental cause of twinkling remains elusive, the distinctive twinkling signature is diagnostically valuable in clinical practice. It can be inferred that if an entity twinkles, it empirically has certain physical features. This work investigates a manipulable polymeric material, polymethyl methacrylate (PMMA), which twinkles and has measurable surface roughness and porosity that likely contribute to twinkling. Comparative investigation of these structural properties and of the twinkling signatures of breast biopsy markers made from PMMA and selected commercially available markers showed how twinkling can improve ultrasound detection of devices intentionally designed to twinkle. While this specific application of detecting breast biopsy markers by twinkling may provide a way to approach an unmet need in the care of patients with breast cancer, this work ultimately provides a platform from which the keys to unlocking the fundamental physics of twinkling can be rigorously explored.

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Factors Associated With Ultrasound Color Doppler Twinkling by Breast Biopsy Markers: In Vitro and Ex Vivo Evaluation of 35 Commercially Available Markers

Lee

Larson

Urban

et al. 2023

American Journal of Roentgenology

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Noninvasive Prediction of Renal Stone Surface Irregularities by Numerical Analysis of the Color Doppler Twinkling Artifact: An Ex Vivo Study

Abstract: It was possible to predict the core roughness of renal stones using the proposed method and the twinkling artifact data acquired from the color Doppler images ex vivo.

Cited by 3 publications

References 46 publications

Doppler twinkling artifact: physical mechanisms and place in diagnostic practice. State of the art

Doppler twinkling artifact: physical mechanisms and place in diagnostic practice. State of the art

Twinkling-guided ultrasound detection of polymethyl methacrylate as a potential breast biopsy marker: a comparative investigation

Factors Associated With Ultrasound Color Doppler Twinkling by Breast Biopsy Markers: In Vitro and Ex Vivo Evaluation of 35 Commercially Available Markers

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