Noninvasive monitoring of peripheral microcirculatory hemodynamics under varying degrees of hypoxia

Ovadia‐Blechman, Zehava; Meilin, Aviram; Rabin, Neta; Eldar, Michael; Castel, David

doi:10.1016/j.resp.2015.05.011

Cited by 28 publications

(15 citation statements)

References 42 publications

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“…This study supports the approach that monitoring of skin microcirculation leads to better diagnostic of systemic cardiovascular and respiratory pathologies [7,22]. Furthermore, during the medical communications era, utilizing this system using telemedicine communication could lead to more effective diagnosis, homecare and even be a lifesaving measure.…”

Section: Resultssupporting

confidence: 77%

“…Based on the results of our previous studies, the LPT system can be used as a reliable noninvasive monitor of microcirculatory hemodynamic variables under different clinical conditions such as hemorrhage followed by fluid transfusion [19], different nitrates and vasoactive drugs at different dosages [20] and different respiration rates [21] and during varying degrees of hypoxia [22].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Peripheral microcirculatory hemodynamic changes in patients with myocardial ischemia

Ovadia‐Blechman

Avrahami

Weizman-Shammai

et al. 2015

Biomedicine & Pharmacotherapy

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Section: Resultssupporting

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Peripheral microcirculatory hemodynamic changes in patients with myocardial ischemia

Ovadia‐Blechman

Avrahami

Weizman-Shammai

et al. 2015

Biomedicine & Pharmacotherapy

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“…The ability to non‐invasively monitor changes in skin microcirculation improves both the diagnosis and treatment of certain diseases. It was already observed that cutaneous haemodynamic variables could reflect local and systemic changes and even predict the development of ischemic stress conditions . Thermography, a non‐ionising, NIV, and low‐cost imaging modality, is based on the detection of infrared (IR) radiation inertly emitted from the surface of a measured object.…”

Section: Introductionmentioning

confidence: 99%

“…It was already observed that cutaneous haemodynamic variables could reflect local and systemic changes and even predict the development of ischemic stress conditions. [36][37][38][39][40][41] Thermography, a non-ionising, NIV, and low-cost imaging modality, is based on the detection of infrared (IR) radiation inertly emitted from the surface of a measured object. Thermal imaging offers the great advantage of real-time temperature measurement and has already been investigated for numerous medical applications.…”

Section: Introductionmentioning

confidence: 99%

Dressings cut to shape alleviate facial tissue loads while using an oxygen mask

Cohen

Ovadia‐Blechman

Hoffer

et al. 2019

International Wound Journal

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Non‐invasive ventilation (NIV) masks are commonly used for respiratory support where intubation or a surgical procedure can be avoided. However, prolonged use of NIV masks involves risk to facial tissues, which are subjected to sustained deformations caused by tightening of the mask and microclimate conditions. The risk of developing such medical device‐related pressure ulcers can be reduced by providing additional cushioning at the mask‐face interface. In this work, we determined differences in facial tissue stresses while using an NIV mask with versus without using dressing cuts (Mepilex Lite; Mölnlycke Health Care, Gothenburg, Sweden). First, we developed a force measurement system that was used to experimentally determine local forces applied to skin at the bridge of the nose, cheeks, and chin in a healthy sample group while using a NIV mask. We further demonstrated facial temperature distributions after use of the mask using infrared thermography. Next, using the finite element method, we delivered the measured compressive forces per site of the face in the model and compared maximal effective stresses in facial tissues with versus without the dressing cuts. The dressings have shown substantial biomechanical effectiveness in alleviating facial tissues deformations and stresses by providing localised cushioning to the tissues at risk.

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“…The level of arterial hemoglobin oxygenation is assessed by oxygen saturation in arterial blood (SaO 2 ), which is the ratio of oxygenated hemoglobin concentration [HbO 2 ] to total hemoglobin concentration in the blood ([HbO 2 ] + [Hb]), usually presented in percentage value (Equation (1)). Normal SaO 2 at sea level is around 97% [1] [2]. HbO SaO % 100 HbO Hb = × + (1) Measuring the oxygen saturation of the blood has extensive clinical implications, for adults, children and premature babies [1].…”

Section: Introductionmentioning

confidence: 99%

The Feasibility of Flat, Portable and Wireless Device for Non-Invasive Peripheral Oxygenation Measurement over the Entire Body

Ovadia‐Blechman¹,

Gino²,

Dandeker³

et al. 2016

JBiSE

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Peripheral oxygenation level (SpO2) can provide vital information on body functions. Continuous monitoring facilitates effective diagnosis and treatment and can even be lifesaving. Clinical device monitor SpO2 using a clip, and measure light transmission through the tissue. This method limits the body locations of the clip's placement and is sensitive to body movement, which hampers continuous SpO2 monitoring during wakefulness or sleep, thus decreasing its usability in clinics and its accessibility in homecare usage. We developed a portable, wireless, flat and low cost prototype for continuous monitoring of SpO2 that overcomes those limitations. The prototype enables convenient measurement in larger variety of body locations by spectrophotometric measurements of changes in the optical reflectance unlike other device that measure absorption through the tissue. The original design and signal processing enable reliable signal acquisition, synchronization and control. An Android's application was developed to provide a user friendly interface for results display on smartphones. The prototype's measurements were compared to commercial device that simultaneously measured heart rate frequency, transcutaneous oxygen tension (tcPO2) and SpO2. The prototype's measurements accurately reflected changes caused by blood pulses, were correlated to the heart rate, and were sensitive to changes in oxygen saturation. Excellent real time behavior and synchronization were demonstrated between the hardware and smartphone software. Our prototype thus enables convenient SpO2 measurement over the entire body, while maintaining accuracy comparable to commercial device. Its smartphone application enables * Corresponding author.Z. Ovadia-Blechman et al. 148accessible and understandable results display to patients, caregivers and healthcare professionals. The application's display and alert calibration flexibility facilitates the prototype's usage in changing medical requirements and for various disease and conditions. A device based on this prototype can monitor continuously and accurately patients' SpO2 without limiting their everyday activities or disturbing their sleep and can thus significantly improve their medical care in both clinics and home.

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Noninvasive monitoring of peripheral microcirculatory hemodynamics under varying degrees of hypoxia

Cited by 28 publications

References 42 publications

Peripheral microcirculatory hemodynamic changes in patients with myocardial ischemia

Peripheral microcirculatory hemodynamic changes in patients with myocardial ischemia

Dressings cut to shape alleviate facial tissue loads while using an oxygen mask

The Feasibility of Flat, Portable and Wireless Device for Non-Invasive Peripheral Oxygenation Measurement over the Entire Body

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