Noninvasive methods to monitor intracranial pressure

Dattilo, Michael

doi:10.1097/wco.0000000000001126

Cited by 4 publications

(3 citation statements)

References 142 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies found that reducing ICP may increase the survival rate among patients with bacterial meningitis [15], which emphasizes the importance of early detection and intervention for ICH. During the neonatal period, Doppler ultrasonography, cerebral blood flow velocity, and near-infrared spectroscopy are common approaches for evaluating ICP [16][17][18][19]. However, the accuracy of these approaches remains problematic, and thus these methods have little validation for clinical use.…”

Section: Discussionmentioning

confidence: 99%

A Novel Nomogram Based on Quantitative MRI and Clinical Features for the Prediction of Neonatal Intracranial Hypertension

Qin,

Liu,

Cao

et al. 2023

Children

View full text Add to dashboard Cite

Intracranial hypertension (ICH) is a serious threat to the health of neonates. However, early and accurate diagnosis of neonatal intracranial hypertension remains a major challenge in clinical practice. In this study, a predictive model based on quantitative magnetic resonance imaging (MRI) data and clinical parameters was developed to identify neonates with a high risk of ICH. Newborns who were suspected of having intracranial lesions were included in our study. We utilized quantitative MRI to obtain the volumetric data of gray matter, white matter, and cerebrospinal fluid. After the MRI examination, a lumbar puncture was performed. The nomogram was constructed by incorporating the volumetric data and clinical features by multivariable logistic regression. The performance of the nomogram was evaluated by discrimination, calibration curve, and decision curve. Clinical parameters and volumetric quantitative MRI data, including postmenstrual age (p = 0.06), weight (p = 0.02), mode of delivery (p = 0.01), and gray matter volume (p = 0.003), were included in and significantly associated with neonatal intracranial hypertension risk. The nomogram showed satisfactory discrimination, with an area under the curve of 0.761. Our results demonstrated that decision curve analysis had promising clinical utility of the nomogram. The nomogram, incorporating clinical and quantitative MRI features, provided an individualized prediction of neonatal intracranial hypertension risk and facilitated decision making guidance for the early diagnosis and treatment for neonatal ICH. External validation from studies using a larger sample size before implementation in the clinical decision-making process is needed.

show abstract

Section: Discussionmentioning

confidence: 99%

A Novel Nomogram Based on Quantitative MRI and Clinical Features for the Prediction of Neonatal Intracranial Hypertension

Qin,

Liu,

Cao

et al. 2023

Children

View full text Add to dashboard Cite

show abstract

“…However, this technique is an invasive procedure, is costly and is restricted to some cases of acute brain injuries. Moreover, it is associated with complications and risks, mainly infection, hemorrhage and obstruction [ 9 , 10 , 11 ]. As BD is a condition of perfusion collapse because of extremely high ICP, one rationale on its monitoring could be the ICP waveforms (ICPW), considering that ICPW change according to reduction in intracranial compliance [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Qualitative Evaluation of Intracranial Pressure Slopes in Patients Undergoing Brain Death Protocol

et al. 2023

View full text Add to dashboard Cite

Background: Due to the importance of not mistaking when determining the brain death (BD) diagnostic, reliable confirmatory exams should be performed to enhance its security. This study aims to evaluate the intracranial pressure (ICP) pulse morphology behavior in brain-dead patients through a noninvasive monitoring system. Methods: A pilot case-control study was conducted in adults that met the BD national protocol criteria. Quantitative parameters from the ICP waveforms, such as the P2/P1 ratio, time-to-peak (TTP) and pulse amplitude (AMP) were extracted and analyzed comparing BD patients and health subjects. Results: Fifteen patients were included, and 6172 waveforms were analyzed. ICP waveforms presented substantial differences amidst BD patients when compared to the control group, especially AMP, which had lower values in patients diagnosed with BD (p < 0.0001) and the TTP median (p < 0.00001), but no significance was found for the P2/P1 ratio (p = 0.8). The area under curve for combination of parameters on the BD prediction was 0.77. Conclusions: In this exploratory study, noninvasive ICP waveforms have shown potential as a screening method in patients with suspected brain death. Future studies should be carried out in a larger population.

show abstract

“…However, this technique is an invasive procedure, costly and restricted to some cases of acute brain injuries. Moreover, it is associated with complications and risks, mainly infection, hemorrhage, and obstruction [9][10][11]. As BD is a condition of perfusion collapse because of extremely high ICP, one rationale on its monitoring could be the ICP waveforms (ICPW), considering that ICPW change according to reduction in intracranial compliance [12].…”

Section: Introductionmentioning

confidence: 99%

Qualitative Evaluation of Intracranial Pressure Slopes in Patients Undergoing Brain Death Protocol

Ideta¹,

Oliveira²,

Gonçalves³

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: Due to the importance of brain death (BD) diagnostic do not mistake, reliable confirmatory exams should be performed to enhance its security. This study aims to evaluate the intracranial pressure (ICP) pulse morphology behavior in brain-dead patients through a noninvasive monitoring system. Methods: A pilot case-control study was conducted in adults that met the BD national protocol criteria. Quantitative data from the ICP waveforms were extracted and analyzed comparing BD patients and health subjects. Results: Fifteen patients were included. ICP waveforms presented substantial differences amidst BD patients when compared to the control group. Moreover, pulse amplitude and time to peak variables values in the case group were also statistically significant. Conclusions: In this exploratory study, noninvasive ICP waveforms have shown potential as a screening method in patients with suspected brain death. Future studies should be carried out in a larger population.

show abstract

Noninvasive methods to monitor intracranial pressure

Cited by 4 publications

References 142 publications

A Novel Nomogram Based on Quantitative MRI and Clinical Features for the Prediction of Neonatal Intracranial Hypertension

A Novel Nomogram Based on Quantitative MRI and Clinical Features for the Prediction of Neonatal Intracranial Hypertension

Qualitative Evaluation of Intracranial Pressure Slopes in Patients Undergoing Brain Death Protocol

Qualitative Evaluation of Intracranial Pressure Slopes in Patients Undergoing Brain Death Protocol

Contact Info

Product

Resources

About