Noninvasive Framework Nucleic Acid Eye Drops for Retinal Administration
Shitai Zhu,
Qinglong Yan,
Lihua Wang
et al.
Abstract:Intravitreal injection is widely employed for the treatment
of
retinal diseases. However, it suffers from various drawbacks, including
ocular trauma, risk of infection, and poor patient compliance due
to frequent administrations. Due to the presence of barriers such
as the cornea, it has been a challenge to develop efficient noninvasive
ophthalmic eye drops that can reach the retina. Framework nucleic
acids (FNAs), known for their excellent biocompatibility and precise,
controllable shape and size, have been e… Show more
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