Noninvasive finding of local repolarization changes in the heart using dipole models and simplified torso geometry

Tyšler, Milan; Svehlikova, Jana

doi:10.1016/j.jelectrocard.2013.03.014

Cited by 11 publications

(9 citation statements)

References 17 publications

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“…The single dipole model and the BEM method were already applied in the ECG inverse solution (Tysler & Svehlikova, 2013 ). The differences between the study by Tysler et al and this work are listed here: (i) The dipole position was predefined in the study of Tysler et al and only three dipole moment components were computed.…”

Section: Discussionmentioning

confidence: 99%

“…The SEMCD is applied in localizing focal activity for WPW (Wolff–Parkinson–White) syndrome, arrhythmogenic centers, and sites of origin of ventricular electrical activation. More studies based on SEMCD were reported on the study of ECG (Armoundas, Feldman, Mukkamala & Cohen, 2003 ; Armoundas, Feldman, Mukkamala, Mullen, et al, 2003 ; Fukuoka et al, 2006 ; Tysler & Svehlikova, 2013 ).…”

Section: Introductionmentioning

confidence: 99%

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A method for magnetocardiography functional localization based on boundary element method and Nelder–Mead simplex algorithm

Jiang

Yang

2021

Noninvasive Electrocardiol

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Background The magnetocardiography (MCG) functional localization can transfer the biomagnetic signal to the electrical activity information inside the heart. The electrical activity is directly related to the physiological function of the heart. Methods This study proposes a practical method for MCG functional localization based on the boundary element method (BEM) and the Nelder–Mead (NM) simplex algorithm. Single equivalent moving current dipole (SEMCD) is served as the equivalent cardiac source. The parameters of SEMCD are adapted using the NM simplex algorithm by fitting the measured MCG with the calculated MCG obtained based on BEM. The SEMCD parameters are solved in the sense that the difference between measured and calculated MCG is minimized. Results The factors affecting the localization accuracy of this BEM–NM method were first explored with synthetic signals. Then, the results with real MCG signals show a good agreement between the SEMCD location and the region where ventricle depolarization starts, demonstrating the feasibility of this idea. Conclusions This is the first three‐dimensional localization of the onset of ventricular depolarization with the BEM–NM method. The method is promising in the noninvasive localization of lesions for heart diseases.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A method for magnetocardiography functional localization based on boundary element method and Nelder–Mead simplex algorithm

Jiang

Yang

2021

Noninvasive Electrocardiol

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“…Mainardi and Sassi [15], [16] reported on a method which calculates an index of repolarization heterogeneity on the heart directly from ECG measurements, based on the so-called dominant T-wave approximation [17]. More in the spirit of our work, Shvehlikova, Lenkova and Tysler developed an inverse method that detected isolated occurrences of TWA on the heart by modeling the TWA source as a set of candidate dipoles distributed on the heart surface and applying a dipole-based inverse solution to BSP to identify the most appropriate locations among those candidates [18], [19].…”

Section: Introductionmentioning

confidence: 99%

A Potential-Based Inverse Spectral Method to Noninvasively Localize Discordant Distributions of Alternans on the Heart From the ECG

Coll‐Font

Erem

Brooks³

2018

IEEE Trans. Biomed. Eng.

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“…Much simpler models are presently being used inside inverse models, which aim at recovering cardiac events from non-invasive signals (Ramanathan et al, 2004; van Dam et al, 2009; Tysler and Svehlikova, 2013; Wang et al, 2013; Erem et al, 2014), and in interactive ECG-simulation tools (van Oosterom et al, 2011). Typically, these models assume predefined propagation velocities and predefined action potential waveforms.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a Rapid Anisotropic Model for ECG Simulation

et al. 2017

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State-of-the-art cardiac electrophysiology models that are able to deliver physiologically motivated activation maps and electrocardiograms (ECGs) can only be solved on high-performance computing architectures. This makes it nearly impossible to adopt such models in clinical practice. ECG imaging tools typically rely on simplified models, but these neglect the anisotropic electric conductivity of the tissue in the forward problem. Moreover, their results are often confined to the heart-torso interface. We propose a forward model that fully accounts for the anisotropic tissue conductivity and produces the standard 12-lead ECG in a few seconds. The activation sequence is approximated with an eikonal model in the 3d myocardium, while the ECG is computed with the lead-field approach. Both solvers were implemented on graphics processing units and massively parallelized. We studied the numerical convergence and scalability of the approach. We also compared the method to the bidomain model in terms of ECGs and activation maps, using a simplified but physiologically motivated geometry and 6 patient-specific anatomies. The proposed methods provided a good approximation of activation maps and ECGs computed with a bidomain model, in only a few seconds. Both solvers scaled very well to high-end hardware. These methods are suitable for use in ECG imaging methods, and may soon become fast enough for use in interactive simulation tools.

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Noninvasive finding of local repolarization changes in the heart using dipole models and simplified torso geometry

Cited by 11 publications

References 17 publications

A method for magnetocardiography functional localization based on boundary element method and Nelder–Mead simplex algorithm

A method for magnetocardiography functional localization based on boundary element method and Nelder–Mead simplex algorithm

A Potential-Based Inverse Spectral Method to Noninvasively Localize Discordant Distributions of Alternans on the Heart From the ECG

Evaluation of a Rapid Anisotropic Model for ECG Simulation

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