Noninvasive estimation of left ventricular filling pressure by e/e′ is a powerful predictor of survival after acute myocardial infarction

Hillis, Graham S.; Møller, Jacob Eifer; Pellikka, Patricia A.; Gersh, Bernard J.; Wright, R. Scott; Ommen, Steve R.; Reeder, Guy S.; Oh, Jae K.

doi:10.1016/j.jacc.2003.07.044

Cited by 478 publications

(180 citation statements)

References 39 publications

(47 reference statements)

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“…23,24 E/E 0 has become a reliable variable for diastolic dysfunction and future cardiac morbidity and mortality. 25 The association of arterial stiffness with LV structure and LV function, particularly diastolic dysfunction, has been studied in patients with hypertension. 26 Given the associations between the atherosclerosis and LV diastolic dysfunction, we also detected the correlation between salusin-alpha and LV diastolic dysfunction.…”

Section: Salusin-alpha Is Associated With LV Diastolic Dysfunction Inmentioning

confidence: 99%

Associations of serum salusin-alpha levels with atherosclerosis and left ventricular diastolic dysfunction in essential hypertension

Wang

et al. 2011

J Hum Hypertens

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Serum salusin-alpha, is decreased in essential hypertension and acute coronary syndrome. The study is aimed to explore whether serum salusin-alpha is associated with atherosclerosis and left ventricular (LV) diastolic dysfunction in essential hypertension. Echocardiography, carotid ultrasonography, brachial-ankle pulse wave velocity (BaPWV) and serum salusin-alpha levels were determined in 60 hypertensive patients (29 with and 31 without carotid plaque) and 30 normotensive controls. Hypertensive patients with plaque, compared with those without plaque or the controls, had the lowest values of salusin-alpha. Then the hypertensive patients were divided into left ventricular hypertrophy (LVH) and non-LVH groups according to the echocardiography. Similarly, hypertensive patients with LVH showed the lowest serum salusinalpha levels. In all subjects, serum salusin-alpha levels were negatively correlated with carotid mean-intimamedia thickness (IMT), BaPWV, left ventricle mass index (LVMI) and E/E 0 (r ¼ À0.488, Po0.001; r ¼ À0.381, Po0.001; r ¼ À0.294, P ¼ 0.006; r ¼ À0.303, P ¼ 0.005; respectively). Serum salusin-alpha levels were independent predictors of BaPWV, carotid strain, carotid distensibility, mean-IMT, LVMI and E 0 /A 0 (b ¼ À0.399, 0.283, 0.237, À0.346, À0.306, 0.469; P ¼ 0.002, 0.031, 0.016, 0.005, 0.012 and 0.001, respectively) in multiple linear regression models. These results suggest that serum salusin-alpha may be associated with atherosclerosis and LV diastolic dysfunction in essential hypertension.

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Section: Salusin-alpha Is Associated With LV Diastolic Dysfunction Inmentioning

confidence: 99%

Associations of serum salusin-alpha levels with atherosclerosis and left ventricular diastolic dysfunction in essential hypertension

Wang

et al. 2011

J Hum Hypertens

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“…Post myocardial infarction (MI), E/E’ is a powerful predictor of survival and E/E’ > 15 is superior as predictor of prognosis to other clinical or echocardiographic variables 107 .…”

Section: E/e' and T E‐e'mentioning

confidence: 99%

Echocardiographic evaluation of diastolic heart failure

Thomas

2010

Australas J Ultrason Med

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“…TDI has been validated extensively in a variety of cardiac pathologies including HF 39 , AMI 40 , hypertension 41 , diabetes 42 and in stress echocardiography 43 where TDI systolic velocities are used as an adjunct to WMSI 44 . The peak systolic septal annular (Sa) or basal septal segmental velocity (Sm) is a sensitive marker of impaired LV systolic function, even in those with a normal LVEF 45 .…”

Section: Newer Parameters and Applicationmentioning

confidence: 99%

Echocardiographic evaluation of systolic heart failure

Thomas

2009

Australas J Ultrason Med

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Echocardiography is the most commonly used modality for evaluating left ventricular size and function in the context of systolic heart failure. Traditional techniques, though extensively used, have their limitations and more recently several newer technologies have emerged that are more reproducible, provide prognostic information, guide therapies and have an important role in monitoring progress. This review will evaluate the traditional and more novel techniques used and briefly provide an overview of the role of echocardiography in guiding and monitoring therapies in patients with systolic heart failure.

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Noninvasive estimation of left ventricular filling pressure by e/e′ is a powerful predictor of survival after acute myocardial infarction

Abstract: E/e' is a powerful predictor of survival after acute MI. An E/e' ratio >15 is superior, in this respect, to other clinical or echocardiographic features. Furthermore, it provides prognostic information incremental to these parameters.

Cited by 478 publications

References 39 publications

Associations of serum salusin-alpha levels with atherosclerosis and left ventricular diastolic dysfunction in essential hypertension

Associations of serum salusin-alpha levels with atherosclerosis and left ventricular diastolic dysfunction in essential hypertension

Echocardiographic evaluation of diastolic heart failure

Echocardiographic evaluation of systolic heart failure

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