Noninfectious Endophthalmitis after Intravitreal Injection of Aflibercept

Abstract

Purpose:To report a case of noninfectious endophthalmitis after intravitreal injection of aflibercept. Case summary: A 67-year-old male patient presented with sudden vision loss 2 days after intravitreal aflibercept injection for neovascular age-related macular degeneration. Mild conjunctival injection and moderate inflammation in the anterior chamber were noted, but he had no ocular pain or hypopyon. The patient was diagnosed with noninfectious endophthalmitis and successfully treated with topical antibiotics and topical steroid eye drops. The infection was apparently cleared at 3 days. At 10 days after the initial presentation, his vision loss resolved completely.