1996
DOI: 10.1016/s0968-0896(96)00226-x
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Nonenzymatic sequence-specific cleavage of duplex DNA via triple-helix formation by homopyrimidine phosphorothioate oligonucleotides

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Cited by 3 publications
(1 citation statement)
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“…In general, three different types of modified oligonucleotides have been described which have increased or total nuclease resistance and still retain triplex-forming capabilities. These include oligonucleotides with α-anomeric ( ) or 2‘-arabino- (), 2‘-fluoro- (), 2‘- O -methyl- ( ), or 2‘- O -aminoethoxy nucleosides (); oligonucleotides containing phosphate-modified internucleotide bonds such as phosphorothioate ( ), methylphosphonate ( ), or cationic linkages ( ); and oligonucleotides containing non-phosphate internucleotide bonds such as carboxamide (), urea ( , ), or riboacetal linkages () and peptide nucleic acids ( ).…”
mentioning
confidence: 99%
“…In general, three different types of modified oligonucleotides have been described which have increased or total nuclease resistance and still retain triplex-forming capabilities. These include oligonucleotides with α-anomeric ( ) or 2‘-arabino- (), 2‘-fluoro- (), 2‘- O -methyl- ( ), or 2‘- O -aminoethoxy nucleosides (); oligonucleotides containing phosphate-modified internucleotide bonds such as phosphorothioate ( ), methylphosphonate ( ), or cationic linkages ( ); and oligonucleotides containing non-phosphate internucleotide bonds such as carboxamide (), urea ( , ), or riboacetal linkages () and peptide nucleic acids ( ).…”
mentioning
confidence: 99%