Noncontrast‐enhanced magnetic resonance angiography and venography imaging with enhanced angiography

Ye, Yongquan; Hu, Jiani; Wu, Dongmei; Haacke, E. Mark

doi:10.1002/jmri.24128

Cited by 29 publications

(29 citation statements)

References 28 publications

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“…When multi‐echo data are available, it is possible to obtain MRA and SWI simultaneously, which are both necessary to depict the cerebral vascular system morphologically and functionally . We have developed a new interleaved double‐echo sequence with arbitrary TEs to achieve simultaneous high‐resolution MRA and venography through enhanced time‐of‐flight (TOF) angiography and SWI, allowing the clear separation of arteries and veins in a single scan. One particular advantage of this sequence is that the interleaved images are precisely aligned to each other, and hence image registration is not required.…”

Section: Data Acquisitionmentioning

confidence: 99%

Susceptibility‐weighted imaging: current status and future directions

Liu¹,

Buch²,

et al. 2016

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Susceptibility weighted imaging (SWI) is a method that uses the intrinsic nature of local magnetic fields to enhance image contrast in order to improve the visibility of various susceptibility sources and to facilitate the diagnostic interpretation. It is also the precursor to the concept of using phase for quantitative susceptibility mapping (QSM). Nowadays, SWI has become a widely used clinical tool to image deoxyhemoglobin in veins, iron deposition in the brain, hemorrhages, microbleeds, and calcification. In this paper, we review the basics of SWI, including data acquisition, data reconstruction and post-processing. In particular, the source of cusp artifacts in phase images is investigated in detail and an improved multi-channel phase data combination algorithm is provided. In addition, we show a few clinical applications of SWI for imaging stroke, traumatic brain injury, carotid vessel wall, siderotic nodules in cirrhotic liver, prostate cancer, prostatic calcification, spinal cord injury and intervertebral disc degeneration. As the clinical applications of SWI continue to expand both in and outside the brain, improving SWI in conjunction with QSM is an important future direction of this technology.

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Section: Data Acquisitionmentioning

confidence: 99%

Susceptibility‐weighted imaging: current status and future directions

Liu¹,

Buch²,

et al. 2016

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“…Susceptibility weighted imaging (SWI) data 26,28,48 were acquired once before the intake of acetazolamide or caffeine and then every 15 min for four time points after the intake. 48,49 Acquiring data at different time points was essential to study the variation in susceptibility values based on the functional dynamics caused by the drug and to select the time point that provided the peak change. The study was approved by the institutional review board of Wayne State University, Detroit, MI, and performed in accordance with the ethical guidelines of the Declaration of Helsinki.…”

Section: Data Acquisitionmentioning

confidence: 99%

Quantifying the changes in oxygen extraction fraction and cerebral activity caused by caffeine and acetazolamide

Buch¹,

Haacke

2016

J Cereb Blood Flow Metab

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A quantitative estimate of cerebral blood oxygen saturation is of critical importance in the investigation of cerebrovascular disease. We aimed to measure the change in venous oxygen saturation (Y) before and after the intake of the vaso-dynamic agents caffeine and acetazolamide with high spatial resolution using susceptibility mapping. Caffeine and acetazolamide were administered on separate days to five healthy volunteers to measure the change in oxygen extraction fraction. The internal streaking artifacts in the susceptibility maps were reduced by giving an initial susceptibility value uniformly to the structure-of-interest, based on a priori information. Using this technique, Y for normal physiological conditions, post-caffeine and post-acetazolamide was measured inside the internal cerebral veins as Y = 69.1 ± 3.3%, Y = 60.5 ± 2.8%, and Y = 79.1 ± 4.0%. This suggests that susceptibility mapping can serve as a sensitive biomarker for measuring reductions in cerebro-vascular reserve through abnormal vascular response. The percentage change in oxygen extraction fraction for caffeine and acetazolamide were found to be +27.0 ± 3.8% and -32.6 ± 2.1%, respectively. Similarly, the relative changes in cerebral blood flow in the presence of caffeine and acetazolamide were found to be -30.3% and + 31.5%, suggesting that the cerebral metabolic rate of oxygen remains stable between normal and challenged brain states for healthy subjects.

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“…As comparison, we also tested several routine and state‐of‐the‐art MRA approaches on all subjects. The comparing methods included: (i) coronal 2D TOF MRA (TR/echo time [TE] = 12/3.7 ms, flip angle = 20°, slice thickness = 1.5 mm with 50% overlap, scan duration = 251 s); (ii) coronal 3D TOF MRA (TR/TE = 12/3.7 ms, flip angle = 20°, scan duration = 251 s); (iii) coronal 3D TOF MRA with fat saturation (FS) pulse (TR/TE = 23/3.7 ms, flip angle = 12°, total scan time = 481 s); (iv) coronal 3D TOF MRA with 1‐2‐1 binomial water excitation (WE) pulse (TR/TE = 12/4.2 ms, flip angle = 12°, scan duration = 251 s); (v) coronal linear subtraction (LS) MRA , which collects both flow compensated and flow dephased images with identical TE in a TR‐interleaved manner. Linear subtraction were done between the two images sets to remove background signal (TR/TE = 17/10.9 ms, flip angle = 12°, VENC value = 1.46 cm/s, scan duration = 363 s); and (vi) sagittal CE‐MRA (TR/TE = 12/3.7 ms, flip angle = 12°, using 0.1 mMol/kg Megavist, scan duration = 251 s) was also collected on two subjects using the same coverage as BORR.…”

Section: Methodsmentioning

confidence: 99%

Retrobulbar magnetic resonance angiography using binomial off‐resonant rectangular (BORR) pulse

Lewis

et al. 2014

Magnetic Resonance in Med

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Noncontrast‐enhanced magnetic resonance angiography and venography imaging with enhanced angiography

Abstract: Using the proposed interleaved double-echo sequence along with the NLS postprocessing method, one can simultaneously obtain both high-quality SWI and significantly enhanced TOF MRA with clear separation of arterial and venous maps.

Cited by 29 publications

References 28 publications

Susceptibility‐weighted imaging: current status and future directions

Susceptibility‐weighted imaging: current status and future directions

Quantifying the changes in oxygen extraction fraction and cerebral activity caused by caffeine and acetazolamide

Retrobulbar magnetic resonance angiography using binomial off‐resonant rectangular (BORR) pulse

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