Noncontact optical sensor for bone fracture diagnostics

Bishitz, Yael; Ozana, Nisan; Beiderman, Yevgeny; Tenner, Felix; Schmidt, Michael; Micó, Vicente; Garcı́a, Javier; Zalevsky, Zeev

doi:10.1364/boe.6.000651

Cited by 16 publications

(10 citation statements)

References 24 publications

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“…This phenomenon (i.e. the frequency response difference between hard and soft tissues) was also proved in Ref [37]. Please note that the range of the excited frequencies is also limited by the frame rate of the camera due to the Nyquist sampling theorem.…”

Section: Signature Of Pigmentary Lesion and Normal Skinsupporting

confidence: 55%

“…The amplitude of the vibrations was measured with the presented technology which is considered to be very precise (nanometric resolution). The sensitivity of the presented approach was proven several times before with different conditions as it is shown in Refs [37][38][39][40][41][42][43][44][45]. Summary of the process is shown in Fig.…”

Section: Theoretical Explanationmentioning

confidence: 99%

“…The tissue is illuminated with a skin safe laser and the reflected secondary speckle patterns are analyzed with a camera [37,38]. The use of such a concept was already demonstrated for non-contact biomedical monitoring including different biomedical parameters such as heart rate [39], non-invasive monitoring of glucose concentration in blood [40,41], remote estimation of alcohol in blood stream [42], blood pulse pressure [43] and measurement of intra ocular pressure [43,45].…”

Section: Introductionmentioning

confidence: 99%

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Optical configuration of pigmented lesion detection by frequency analysis of skin speckle patterns

Bishitz¹,

Ozana²,

Schwarz³

et al. 2016

Biomed. Opt. Express

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Abstract:In this paper we present a novel approach of realizing a safe, simple, and inexpensive sensor applicable to pigmented lesions detection. The approach is based on temporal tracking of back-reflected secondary speckle patterns generated while illuminating the affected area with a laser and applying periodic pressure to the surface via a controlled vibration source. When applied to pigmented lesions, the technique is superior to visual examination in avoiding many false positives and resultant unnecessary biopsies. Applying a series of different vibration frequencies at the examined tissue and analyzing the 2-D time varying speckle patterns in response to the applied periodic pressure creates a unique signature for each and different pigmented lesion. Analyzing these signatures is the first step toward detection of malignant melanoma. In this paper we present preliminary experiments that show the validity of the developed sensor for the classification of pigmented lesions.

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Section: Signature Of Pigmentary Lesion and Normal Skinsupporting

confidence: 55%

Section: Theoretical Explanationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Optical configuration of pigmented lesion detection by frequency analysis of skin speckle patterns

Bishitz¹,

Ozana²,

Schwarz³

et al. 2016

Biomed. Opt. Express

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“…Ideally, in vivo fatigue cracking would be monitored on a yearly basis using radiation-free and affordable imaging that achieves the sensitivity currently available only with MRI or high-resolution computed tomography. An optical sensor consisting of a laser and a camera that can affordably distinguish between broken and unbroken bones without radiation 154 shows promise, but this technique has not yet been tested on insufficiency fractures.…”

Section: Prevention and Monitoring Of Insufficiency Fracturesmentioning

confidence: 99%

Fatigue as the missing link between bone fragility and fracture

et al. 2018

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“…10 There are several effects that can change the speckle field such as temporal skin movement, a very useful effect for biomedical monitoring. [11][12][13][14][15][16][17] Another effect is the change in the incident wavefront caused by the change in the polarization state. This change will also lead to changes in the speckle pattern.…”

Section: Introductionmentioning

confidence: 99%

Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect

et al. 2016

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We experimentally verify a speckle-based technique for noncontact measurement of glucose concentration in the bloodstream. The final device is intended to be a single wristwatch-style device containing a laser, a camera, and an alternating current (ac) electromagnet generated by a solenoid. The experiments presented are performed in vitro as proof of the concept. When a glucose substance is inserted into a solenoid generating an ac magnetic field, it exhibits Faraday rotation, which affects the temporal changes of the secondary speckle pattern distributions. The temporal frequency resulting from the ac magnetic field was found to have a lock-in amplification role, which increased the observability of the relatively small magneto-optic effect. Experimental results to support the proposed concept are presented.

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Noncontact optical sensor for bone fracture diagnostics

Cited by 16 publications

References 24 publications

Optical configuration of pigmented lesion detection by frequency analysis of skin speckle patterns

Optical configuration of pigmented lesion detection by frequency analysis of skin speckle patterns

Fatigue as the missing link between bone fragility and fracture

Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect

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