Noncatalyzed Radical Chain Oxidation: Cumene Hydroperoxide

A new highly active La2O3–CuO–MgO catalyst for the synthesis of cumyl peroxide by catalytic oxidation

“…55 In the reaction process, the dissociation enthalpy of the O-H bond is 104 kcal mol À1 in benzol RO-H and 88 kcal mol À1 in CHP ROO-H. 56 The rate of extracting hydrogen atoms (S2) from IPB molecules by ROc free radicals is much faster than that of hydrogen abstraction reaction (S1) between ROOc and IPB. 3 The formation of CHP and Rc (S2) becomes the control step of the whole radical chain reaction. Improving transformation capability is an efficient way to effectively stimulate the tertiary carbon-hydrogen bond for IPB.…”

“…1 For example, the oxidation of cumene is one of the important way to produce cumene hydroperoxide (CHP), phenol, and acetone in industry. 2,3 CHP is used in industry as an initiator for chain autoxidation and polymerization reactions, an accelerator for rubber vulcanization, an oxidant in ne chemicals, and in polymer synthesis. 4,5 Phenol is an important raw material for phenol resins, perfumes, medicines, agricultural chemicals, and many other industries.…”

Ionic liquids of superior thermal stability. Validation of PPh4+ as an organic cation of impressive thermodynamic durability

“…In separate experiments, samples of each IL were heated in air to 200 C, 250 C, and 300 C in a Thermolyne FB-1315M furnace for a 96 hour period, with each sample then being analysed post-heating by 1 H-, 13 C-, 31 P-, and 19 F-NMR (JEOL ECA 500), as well as by electrospray ionization mass spectra (Ther-moFisher LTQ-Velos). This particular thermoanalytic approach developed specically to subject ILs to harsh, 'real-world' conditionswas conceived and its utility validated by Fox et al at Savannah River National Laboratory, before being employed by our group.…”

Strategy for the Use of Molecular Oxygen in Organic Synthesis

“…On the other hand, industrial synthesis of phenol by the cumene process is a typical example of the use of O 2 as an oxygen atom source because two oxygen atoms are incorporated into an organic molecule (Scheme 1b). 3 Autooxidation of cumene by O 2 produces the corresponding hydroperoxide as a synthetic intermediate in this process, which is converted into phenol and acetone by the following Hock rearrangement by acidic hydrolysis. Thus, the character of O 2 as an oxygen atom source offers methods for functionalization of organic molecules.…”