A review of the literature concerning reactions of ozone with amines has given rise to the working hypothesis that these reactions all involve initially the electrophilic attack of ozone to give an adduct for which at least three different reaction routes are available: loss of molecular oxygen to give an amine oxide or further reaction products thereof, an intramolecular oxidation of a side chain, and dissociation to nitrogen cation radicals and the ozonate anion radical, followed by further reactions of these. Results from ozonations of tert-butylamine and tri-n-butylamine, which furnish additional evidence for the above competitions, are described.>Tphe literature suggests several ways in which ozone reacts with amines.