Nonablative Laser and Light Therapies for Skin Rejuvenation

Kim, Karen H.; Geronemus, Roy G.

doi:10.1001/archfaci.6.6.398

Cited by 76 publications

(46 citation statements)

References 47 publications

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“…As interest in aging and rejuvenation continues to increase, various dermal fillers, lasers, light source technologies, and RF devices are now being developed4,5,6,7,8, with any number of combination treatments also reported3,9,10,11,12. In the present study, we evaluated the safety and efficacy of a combination regimen of HA filler and a new needle RF device.…”

Section: Discussionmentioning

confidence: 99%

The Efficacy, Longevity, and Safety of Combined Radiofrequency Treatment and Hyaluronic Acid Filler for Skin Rejuvenation

et al. 2014

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BackgroundRecent advances in hyaluronic acid (HA) fillers and radiofrequency (RF) devices have been made in the context of skin rejuvenation and cosmetic surgery. Moreover, combination regimens with both techniques are currently being developed.ObjectiveThe present study was designed to examine the clinical and histologic effects of a new needle that incorporates an RF device for HA injections.MethodsA new intradermal needle RF device (INNOfill; Pacific Pharma, Korea) was assessed in the present study. In the animal arm, procollagen production was measured by using enzyme-linked immunosorbent assay, the filler volume was quantified by incorporating a dye with filler, and the filler distribution was assessed through the changes in tissue structure. In the human arm, the efficacy of the combination regimen was assessed by using the wrinkle severity rating scale (WSRS).ResultsIn the animal study, RF treatment increased procollagen production in a time-dependent fashion. The total volume was significantly increased with the RF treatment when compared with the filler injections alone, and lasted for up to 7 weeks after treatment. Additionally, the filler distribution was reduced in animals treated with RF when compared with the untreated group. In the human study, the nasolabial folds of subjects treated with RF before filler injections exhibited a significantly greater change in the WSRS score from baseline when compared with the nasolabial folds treated with filler injections alone.ConclusionA new device incorporating RF treatment before HA filler injection may represent a biocompatible and long-lasting advance in skin rejuvenation.

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Section: Discussionmentioning

confidence: 99%

The Efficacy, Longevity, and Safety of Combined Radiofrequency Treatment and Hyaluronic Acid Filler for Skin Rejuvenation

et al. 2014

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“…Similar to the 1320‐nm Nd:YAG laser, the 1064‐nm wavelength deposits nonselective heat into the dermis with a minimal affinity for melanin. The short pulse duration in the nanosecond range is thought to confine injury to the intended target and minimize heat diffusion to other structures 8 . Goldberg et al .…”

Section: ‐Nm Nd:yag Lasermentioning

confidence: 99%

“…Different nonablative light sources and laser technologies are currently available (Table 1). Lasers can be classified in two groups based on their wavelengths: lasers emitting light in the visible range, and those emitting in the infrared range 7,8 (Fig. 1).…”

Section: Introductionmentioning

confidence: 99%

Nonablative lasers

Nouri

Rivas

Bouzari

et al. 2006

J of Cosmetic Dermatology

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The trend toward minimally invasive rejuvenation techniques has led to the widespread use of nonablative lasers. Nonablative lasers can be classified in two groups based on their wavelengths: lasers emitting light in the visible range, and those emitting in the infrared range. In this review, different laser and intense pulsed light (IPL) systems are presented and critically discussed along with findings of the studies in the literature.

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“…Through its action on the epidermal and dermal layers, these lasers promote a healing response through activation of fibroblasts, and enhanced collagen and elastin neoformation. This process repairs and restores damaged skin tissues .…”

Section: Introductionmentioning

confidence: 99%