Non-Verbal Cognitive Abilities in Children and Adolescents Affected by Migraine and Tension-Type Headache: An Observational Study Using the Leiter-3

Margari, Lucia; Palumbi, Roberto; Lecce, Paola Alessandra; Craig, Francesco; Simone, Marta; Margari, Mariella; Seccia, Silvana M. C.; Buttiglione, Maura

doi:10.3389/fneur.2018.00078

Cited by 4 publications

(5 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In disagreement with previous studies, Margari et al ( 39 ) reported the absence of significant differences between patients with primary headache and controls in “Forward Memory,” “Reverse Memory” and “Non-verbal Memory” subtests scores, issued from the cognitive non-verbal test “Leiter-3” ( 57 ). However, the study described a significant association of frequency of the attacks and headache disability with non-verbal memory abilities, suggesting that higher headache disability may have a significant impact on specific cognitive domains, such as the non-verbal memory.…”

Section: Resultsmentioning

confidence: 81%

“…In particular, comparing the performance of children suffering from migraine with (n. 17) and without aura (n. 31), the authors did not identify significant differences in the distribution of Progressive Matrices scores between the groups of patients. In a more recent study, Margari et al evaluated the non-verbal intelligence abilities, including fluid intelligence, attention skills and non-verbal memory, in pediatric patients with primary headache ( 39 ). Thirty-five children suffering from migraine (n. 26) or TTH (n. 9) and 23 healthy subjects were evaluated with the cognitive battery “Leiter-3” ( 57 ).…”

Section: Resultsmentioning

confidence: 99%

“…Data on the role of migraine features on memory abilities in pediatric patients are sparse ( Table 1 ). To the best of our knowledge, in addition to the above mentioned studies ( 39 , 45 ), only Calandre et al ( 32 ) explored this topic. In a sample of 28 adults and 32 pediatric patients with migraine, the authors described an impairment of short- and long-term visual memory, verbal memory, and working memory, related to frequency of the attacks and headache history.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Interictal Cognitive Performance in Children and Adolescents With Primary Headache: A Narrative Review

et al. 2022

View full text Add to dashboard Cite

Primary headache is a very common and disabling disease. The burden of pain and recurrent attacks may lead to a poor quality of life, anxiety and depression. An increased risk of low functioning and curricular performances in young patients with primary headache has been described. The mechanisms underlying the relationship between migraine and poor school achievement may be various and could be a reflection of weak cognitive skills. Data concerning the cognitive functioning in the free pain interval in pediatric age are under-investigated and results are far from conclusive. The present review article suggests that, though considered a benign disease, pediatric migraine may be associated to altered neuropsychological functioning in the interictal phase. Although children and adolescents with migraine generally have a normal intelligence, they may show a not homogeneous cognitive profile, characterized by possible difficulties in verbal skills, in particular comprehension abilities. Pediatric primary headache may present altered neuropsychological functioning involving attentional resources, processing speed and memory, particularly verbal memory. Given the impact that this disease can have on school performance and the tendency to persist from childhood to adulthood, a cognitive screening in young patients affected by primary headache is pivotal. Additional neuropsychological research using more homogenous methods is needed.

show abstract

Section: Resultsmentioning

confidence: 81%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Interictal Cognitive Performance in Children and Adolescents With Primary Headache: A Narrative Review

et al. 2022

View full text Add to dashboard Cite

show abstract

“…At the time of enrollment children were 3-11 years old, had normal hearing in both ears (i.e., 25 dB HL or better at 0.5, 1.0, 2.0, and 4.0 kHz), no history of exposure to traumatic noise, and normal tympanometry. Children with a history of mental illness, neurological disease, or loss of consciousness were excluded, as these factors impact performance on CATs [19][20][21] . HIV status was con rmed in children using medical records or a rapid HIV test and recon rmed using an ELISA assay.…”

Section: Inclusion Criteriamentioning

confidence: 99%

Central auditory test performance predicts future neurocognitive function in children living with and without HIV

Joseph,

Niemczak,

Lichtenstein

et al. 2023

Preprint

View full text Add to dashboard Cite

Tests of the brain’s ability to process sound (central auditory tests) correlate with overall measure of neurocognitive performance. In the developing world where resources to do detailed cognitive testing is limited, objective tests that use the central auditory system may provide a novel and useful way to track neurocognitive performance. This could be particularly useful for children with HIV. To assess this, we examined whether central auditory tests given early in a child’s life could predict tests of later neurocognitive performance. We used a machine learning technique to incorporate other factors known to affect performance on neurocognitive tests, such as education. The results show that central auditory tests are useful predictors of neurocognitive performance and perform as well or in some cases better than factors such as education. Central auditory tests may offer an objective way to track neurocognitive performance in children living with HIV.

show abstract

“…Our own research group came to similar conclusions (6–8). Of the most recent studies, Margari and colleagues showed that both migraine and tension-type headache affect non-verbal cognitive abilities in children and adolescents (9). Termine and co-workers, themselves corroborating the presence and seriousness of the problem in their review, add that “…migraine-related cognitive deficits may interfere with functioning levels across several settings”, and suggest that “[a] careful analysis of cognitive impairment in the context of migraine is pivotal for making informed decisions on the most appropriate care pathways” (10).…”

Section: Introductionmentioning

confidence: 99%

Visually guided associative learning in pediatric and adult migraine without aura

et al. 2020

View full text Add to dashboard Cite

Introduction The Rutgers Acquired Equivalence Test is a visually guided equivalence learning paradigm that involves rule acquisition and generalization. Earlier we found impaired performance in this paradigm among adult migraine patients without aura. The aim of the study was to investigate if similar impairments can be found already in the pediatric form of the disease and to compare the performance of the pediatric study population with that of an adult study population. We hypothesized that the deficits observed in adults would be observable already in the pediatric population. Methods Twenty-seven children and adolescents newly diagnosed with migraine without aura and 27 age- and sex-matched healthy controls were tested with the Rutgers Acquired Equivalence Test. Their performance data were compared to each other and those of an earlier adult study population involving 22 patients and 22 age- and sex-matched healthy controls. Four parameters characterizing performance in the two main phases of the paradigm were calculated for each of the four groups. Performance parameters were compared with Mann-Whitney U test. Results In contrast to the decreased performance of the adult patients in the Rutgers Acquired Equivalence Test, no significant difference was found between pediatric patients and controls in any phase of the paradigm. Conclusion Children living with migraine without aura do not exhibit the same cognitive deficits in the Rutgers Acquired Equivalence Test as their adult counterparts. It can be hypothesized that the deficit of equivalence learning is not an inherent feature of the migrainous cognitive profile, rather the result of the interference of the disease with normal development.

show abstract

Non-Verbal Cognitive Abilities in Children and Adolescents Affected by Migraine and Tension-Type Headache: An Observational Study Using the Leiter-3

Cited by 4 publications

References 27 publications

Interictal Cognitive Performance in Children and Adolescents With Primary Headache: A Narrative Review

Interictal Cognitive Performance in Children and Adolescents With Primary Headache: A Narrative Review

Central auditory test performance predicts future neurocognitive function in children living with and without HIV

Visually guided associative learning in pediatric and adult migraine without aura

Contact Info

Product

Resources

About