Non-Union Op Fractures

Lacey, James T.

doi:10.1097/00000658-192906000-00002

Cited by 2 publications

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“…Although gaining more attention in recent years, the importance of the vascular supply to the skeleton has not undergone historical indifference (Lacey 1929; Brookes 1957; Brookes & Revell 1998). Another pioneer investigator stated that “intraosseous blood flow gives life to bone, just as intracerebral blood flow gives life to the brain and coronary blood flow life to the heart” (Laroche 2002).…”

Section: Introductionmentioning

confidence: 99%

Mechanical, hormonal and metabolic influences on blood vessels, blood flow and bone

Prisby

2017

Journal of Endocrinology

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Bone tissue is highly vascularized due to the various roles bone blood vessels play in bone and bone marrow function. For example, the vascular system is critical for bone development, maintenance and repair, and provides O2, nutrients, waste elimination, systemic hormones, and precursor cells for bone remodeling. Further, bone blood vessels serve as egress and ingress routes for blood and immune cells to and from the bone marrow. It is becoming increasingly clear that the vascular and skeletal systems are intimately linked in metabolic regulation and physiological and pathological processes. This review examines how agents such as mechanical loading, parathyroid hormone, estrogen, vitamin D and calcitonin, all considered anabolic for bone, have tremendous impacts on the bone vasculature. In fact, these agents influence bone blood vessels prior to impacting bone. Further, data reveal strong associations between vasodilator capacity of bone blood vessels and trabecular bone volume, and poor associations between estrogen status and uterine mass and trabecular bone volume. Additionally, this review highlights the importance of the bone microcirculation, particularly the vascular endothelium and NO-mediated signaling, in the regulation of bone blood flow, bone interstitial fluid flow and pressure, and the paracrine signaling of bone cells. Finally, the vascular endothelium as a mediator of bone health and disease is considered.

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Section: Introductionmentioning

confidence: 99%

Mechanical, hormonal and metabolic influences on blood vessels, blood flow and bone

Prisby

2017

Journal of Endocrinology

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“…129 Nicola Lacey has argued that a notion of responsibility based on the character of the accused remains part of modern English criminal process, albeit`underground' and not quite acknowledged. 130 On the other hand, in France, the pervasive influence of character may be much less evident in the routine and low-profile cases coming before the Tribunal Correctionnel or the Tribunal de Police, where the examination of character is much more cursory than before the Cour d'Assises. A recent reform has seen the introduction of the comparution sur reconnaisance pre Âalable de culpabilite Â (appearance after a preliminary acceptance of guilt).…”

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confidence: 99%

State, Citizen, and Character in French Criminal Process

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2006

Journal of Law and Society

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This paper charts some major differences in the way in which evidence of the defendant's character is treated in France when compared with practice in England and Wales. Such evidence is more pervasive and visible (especially in the most serious cases) and its relevance is more broadly defined. Further, its presentation is shaped by a developed and positive conception of the French citizen. In part, these differences may be explained by differences in procedural tradition: the unitary trial structure in France, the dominance of fact-finding by the professional judiciary, and the rejection of general exclusionary rules of evidence. But a full explanation requires French legal culture to be understood in the context of French political culture. This reveals a very different conception of relations between state and citizen to that of AngloSaxon liberalism. As a result the legitimacy of trial is seen in terms of the rehabilitation of the accused as a citizen of the state rather than simply the punishment of a particular infraction.

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Non-Union Op Fractures

Cited by 2 publications

References 0 publications

Mechanical, hormonal and metabolic influences on blood vessels, blood flow and bone

Mechanical, hormonal and metabolic influences on blood vessels, blood flow and bone

State, Citizen, and Character in French Criminal Process

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