Non-typhoidSalmonella bacteraemia in Greater Copenhagen 1984 to 1988

Abstract

A retrospective survey of non-typhoid Salmonella bacteraemia in the period 1984 to 1988 was carried out by the five departments of clinical microbiology in Greater Copenhagen. A total of 168 patients were identified. A gradual increase was observed from 11 cases in 1984 to 58 cases in 1988. The corresponding incidence per 100,000 inhabitants in Copenhagen rose from 0.9 in 1984 to 5.0 in 1988. During the same period the total registered incidence of human Salmonella infections in Denmark increased from 17.6 to 67.4 per 100,000 inhabitants. The serotype most often isolated from bacteraemic patients was Salmonella dublin followed by Salmonella enteritidis and Salmonella typhimurium. Salmonella dublin demonstrated enhanced invasive and pathogenic properties. Predisposing factors were present in 56% of the patients; the most common was malignant disease. A fatal or complicated course of the bacteraemia was observed more frequently in patients with underlying diseases than in persons who had previously been healthy. A total of 17% of the patients died; one-fifth of these had a ruptured aortic aneurysm. It is concluded that the substantial increase in the number of cases and the often serious course taken by the infection demonstrate a need for increased efforts at prophylaxis.

Antimicrobial resistance of Salmonella isolates in a Spanish hospital

“…The relative proportion of Salmonella serogroups and serotypes isolated at a single geographic area or hospital is very variable (5,16,27). Our study, as well as other studies, proves that different serogroups have different patterns of resistance, with serogroups B4,5 and C7 usually being more resistant than serogroup Dg (6).…”

Clinical Review of Nontyphoid Salmonella Infections from 1991 to 1999 in a Danish Country

“…However, even among patients 5-60 years old without a known risk factor, ∼25% were admitted to the hospital, mainly because of moderate dehydration. Bacteremia was seen in as many as 12% of the patients admitted to the hospital and disposed patients to other extraintestinal complications [13][14][15]. Beside extraintestinal complications, intestinal complications and unnecessary surgical procedures to treat suspected acute abdominal conditions (appendectomies and laparoscopies without pathologic findings other than mesenteric lymphadenitis) also contributed to morbidity and mortality.…”

Non‐typhoidal Salmonella bacteraemia: clinical features and risk factors

“…1988; Fischl et al 1986; Glaser et al 1985; Lester et al 1991; Levine et al 1991;Nadelman 1985;Pithie et al 1993) have reported an increasing incidence of non-typhoidal Salmonella bacteraemia, especially in patients infected with human immunodeficiency virus (HIV). In Thailand, the annual reports from the W H O Salmonella and Shigella Center, Department of Medical Science, Ministry of Public Health reveal by a passive surveillance system that the average number of human isolates of Salmonella was 2500 p a .…”