Non-toxigenic Vibrio cholerae non-O1/non-O139 pseudo-bacteraemia in a neonate: A case report

Abstract

Toxigenic Vibrio cholerae O1/O139 is causative of cholera, which is a well characterised potentially epidemic gastrointestinal disease. Less is known about the pathogenesis and clinical presentation of non-toxigenic V. cholerae non-O1/non-O139, although they are increasingly implicated in human disease globally, have been isolated from various South African water sources and can contaminate the environment. The authors describe a case of pseudo-bacteraemia with non-toxigenic V. cholerae non-O1/non-O139 in a neonate.

Vibrio cholerae Bacteremia: An Enigma in Cholera-Endemic African Countries

“…Most of these cases (45%) originated in Taiwan, 20% in the United States, and 6% in Spain. Although the number of cases has risen worldwide in recent years [5,8,9], only four documented reports of V. cholerae bacteremia have been confirmed in Africa, specifically in Malawi, Mauritius, and South Africa [10][11][12][13]. Four other reports could be traced to African origin but diagnosed and/or confirmed in Europe [7,[14][15][16].…”

“…It is not well established if the rare occurrence of reported V. cholerae bacteremia is a true reflection of the epidemiological situation in Africa. V. cholerae bacteremia have been confirmed in Africa, specifically in Malawi, Mauritius, and South Africa [10][11][12][13]. Four other reports could be traced to African origin but diagnosed and/or confirmed in Europe [7,[14][15][16].…”

“…Pakistan, China, Belgium, Lebanon, USA, Saudi Arabia, South Africa, India, Oman, Colombia 34[5,8,9,13,[90][91][92][93][94][95][96][97][98][99][100][101][102][103][104] …”