Non-toxic Polymeric Dots with the Strong Protein-Driven Enhancement of One- and Two-Photon Excited Emission for Sensitive and Non-destructive Albumin Sensing

Abstract

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Strongly Emitting Folic Acid-Derived Carbon Nanodots for One- and Two-Photon Imaging of Lyotropic Myelin Figures

“…92,93 The TPE fluorescence band of the FA CNDs is red-shifted (by 17 nm) with respect to their OPEF spectra (Figure 3f). Such a feature was reported for a variety of fluorescent species containing polymeric sub-structures, including other CNDs, 93 polymer dots (PDs), 30 peptide aggregate forms (i.e., amyloids), 94 etc. 2.5.…”

“…30−36 CDs are a versatile class of carbon nanomaterials with unique applicative properties: high biocompatibility, no cytotoxicity, 30,34,37 facile and low-cost fabrication methods, 38−40 long-term stability, 41 and remarkable linear 42−44 and non-linear optical properties. 30 They also overcome many limitations of conventional fluorescent lipid probes (e.g., the Nile red dye), such as broad emission spectrum, small Stokes shift, and photobleaching. 45−47 Hybrid systems consisting of phospholipids and highly fluorescent CDs have already been successfully applied to research on liposomes, e.g., to investigate the bilayer dynamics 19,48 and formation of lipid rafts.…”

“…CDs are a versatile class of carbon nanomaterials with unique applicative properties: high biocompatibility, no cytotoxicity, ,, facile and low-cost fabrication methods, − long-term stability, and remarkable linear − and non-linear optical properties . They also overcome many limitations of conventional fluorescent lipid probes (e.g., the Nile red dye), such as broad emission spectrum, small Stokes shift, and photobleaching. − …”

High quantum yield carbon dots and nitrogen-doped carbon dots as fluorescent probes for spectroscopic dopamine detection in human serum

“…21 Of all these techniques used, fluorescence assays have been found to be of the foremost importance due to their, bright emission, better sensitivity, and non-destructive nature. 22…”

“…21 Of all these techniques used, fluorescence assays have been found to be of the foremost importance due to their, bright emission, better sensitivity, and non-destructive nature. 22 Recently CD and their doped nanostructures have been found to be promising fluorescence probes in the sensing and detection of DA. Baruah et al created CD that demonstrated DA sensing with a detection limit of 33 mM.…”