Non-targeted analysis of unknown volatile components in scented stationery via headspace GC-Orbitrap MS

Li, Hongyan; Liu, Yahui; Wang, Zhijuan; Zhang, Qing; Xing, Jiangtao; Bai, Hua; Lv, Qing

doi:10.1016/j.talanta.2022.123285

Cited by 11 publications

(4 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Separations were performed on a weak polar HP-5 MS column (30 m × 0.25 mm × 0.25 μm) (Agilent Technologies, California, USA) using the following temperature program: 40 °C (held for 1 min) and 5 °C/min to 160 °C and then 20 °C/min to 250 °C (held for 5 min). This instrumental condition has been maturely applied in our previous studies on nontarget analysis. , …”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Screening and Evaluation of Children’s Sensitively Toxic Chemicals in New Mosquito Repellent Products Based on a Nationwide Investigation

Liu,

Jin,

et al. 2024

Environ. Sci. Technol.

Self Cite

View full text Add to dashboard Cite

New mosquito repellent products (NMRPs) are emerging popular repellents among children. There are increasing reports on children's sensitization reactions caused by NMRPs, while regulations on their productions, sales, or usage are still lacking. One of the reasons could be the missing comprehensive risk assessment. We first conducted a nationwide investigation on children's NMRP usage preferences. Then, we high-throughput screened volatile or semivolatile organic chemicals (VOCs/ SVOCs) in five representative NMRPs by the headspace gas chromatography−orbitrap high-resolution mass spectrometry analytical method. After that, toxic compounds were recognized based on the toxicity forecaster (ToxCast) database. A total of 277 VOCs/SVOCs were recognized, and 70 of them were identified as toxic compounds. In a combination of concentrations, toxicities, absorption, distribution, metabolism, and excretion characteristics in the body, 28 chemicals were finally proposed as priority-controlled compounds in NMRPs. Exposure risks of recognized toxic chemicals through NMRPs by inhalation and dermal intake for children across the country were also assessed. Average daily intakes were in the range of 0.20−7.31 mg/kg/day for children in different provinces, and the children in southeastern coastal provinces were found to face higher exposure risks. By controlling the high-priority chemicals, the risks were expected to be reduced by about 46.8% on average. Results of this study are therefore believed to evaluate exposure risks, encourage safe production, and promote reasonable management of NMRPs.

show abstract

Section: Methodsmentioning

confidence: 99%

“…This instrumental condition has been maturely applied in our previous studies on nontarget analysis. 38,39 MS acquisition with full scan mode was conducted at an m/z range of 40−500. Each sample was analyzed in both the EI mode and CI mode.…”

Section: ■ Materials and Methodsmentioning

confidence: 99%

Screening and Evaluation of Children’s Sensitively Toxic Chemicals in New Mosquito Repellent Products Based on a Nationwide Investigation

Liu,

Jin,

et al. 2024

Environ. Sci. Technol.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Environmental chemicals have been identified using NTA in other unclassified consumer products such as stationary [ 85 ], clothing [ 86 ], personal care products [ 87 ], and tobacco products [ 88 ]. Phillips et al utilized a broad sampling scheme to identify environmental chemicals in a wide variety of consumer products [ 4 ].…”

Section: Characterization Of Exposure Sources Using Ntamentioning

confidence: 99%

Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome

Manz

Feerick

Braun

et al. 2023

J Expo Sci Environ Epidemiol

View full text Add to dashboard Cite

Non-targeted analysis (NTA) and suspect screening analysis (SSA) are powerful techniques that rely on high-resolution mass spectrometry (HRMS) and computational tools to detect and identify unknown or suspected chemicals in the exposome. Fully understanding the chemical exposome requires characterization of both environmental media and human specimens. As such, we conducted a review to examine the use of different NTA and SSA methods in various exposure media and human samples, including the results and chemicals detected. The literature review was conducted by searching literature databases, such as PubMed and Web of Science, for keywords, such as “non-targeted analysis”, “suspect screening analysis” and the exposure media. Sources of human exposure to environmental chemicals discussed in this review include water, air, soil/sediment, dust, and food and consumer products. The use of NTA for exposure discovery in human biospecimen is also reviewed. The chemical space that has been captured using NTA varies by media analyzed and analytical platform. In each media the chemicals that were frequently detected using NTA were: per- and polyfluoroalkyl substances (PFAS) and pharmaceuticals in water, pesticides and polyaromatic hydrocarbons (PAHs) in soil and sediment, volatile and semi-volatile organic compounds in air, flame retardants in dust, plasticizers in consumer products, and plasticizers, pesticides, and halogenated compounds in human samples. Some studies reviewed herein used both liquid chromatography (LC) and gas chromatography (GC) HRMS to increase the detected chemical space (16%); however, the majority (51%) only used LC-HRMS and fewer used GC-HRMS (32%). Finally, we identify knowledge and technology gaps that must be overcome to fully assess potential chemical exposures using NTA. Understanding the chemical space is essential to identifying and prioritizing gaps in our understanding of exposure sources and prior exposures. Impact statement This review examines the results and chemicals detected by analyzing exposure media and human samples using high-resolution mass spectrometry based non-targeted analysis (NTA) and suspect screening analysis (SSA).

show abstract

“…The chemiluminescence sulfur detector lacks a high detection sensitivity on sulfur compounds, whereas sulfur compounds analyzed by a pulsed flame photometric detector can only be measured under a limited concentration range [ 11 , 12 ]. Gas chromatography–Orbitrap–mass spectrometry (GC-Orbitrap-MS) has gained much attention in identifying and quantifying trace volatiles in the food science area since Orbitrap-MS possesses a better mass accuracy and relative ion abundance consistency under a wide concentration range of sulfur volatiles [ 13 , 14 ]. Therefore, GC-Orbitrap-MS and GC-quadrupole mass spectrometry (GC-qMS) were used in the present study for the analysis of sulfur volatiles and other volatile compounds in passion fruit wine, respectively.…”

Section: Introductionmentioning

confidence: 99%

Aromatic Characteristics of Passion Fruit Wines Measured by E-Nose, GC-Quadrupole MS, GC-Orbitrap-MS and Sensory Evaluation

Liu

Zhu

et al. 2022

Foods

View full text Add to dashboard Cite

This study investigated the volatile composition and aromatic features of passion fruit wines using a combination of gas chromatography–quadrupole mass spectrometry (GC-qMS), gas chromatography–Orbitrap–mass spectrometry (GC-Orbitrap-MS), electronic nose (E-nose) and sensory evaluation. The results showed that these passion fruit wines possessed different aromatic features confirmed by E-nose. Seventeen sulfur compounds and seventy-eight volatiles were detected in these passion fruit wines using GC-Orbitrap-MS and GC-qMS, respectively. Forty-four volatiles significantly contributed to the overall wine aroma. These wines possessed passion fruit, mango, green apple, lemon and floral aromas confirmed by sensory evaluation. The partial least squares regression analysis indicated that sulfides, esters and terpenes, and terpenes mainly correlated to the passion fruit, mango and green apple aroma, respectively. Sulfur compounds significantly affected the aroma of passion fruit wine. The findings in this study could provide useful insight toward the quality control of passion fruit wine.

show abstract

Non-targeted analysis of unknown volatile components in scented stationery via headspace GC-Orbitrap MS

Cited by 11 publications

References 19 publications

Screening and Evaluation of Children’s Sensitively Toxic Chemicals in New Mosquito Repellent Products Based on a Nationwide Investigation

Screening and Evaluation of Children’s Sensitively Toxic Chemicals in New Mosquito Repellent Products Based on a Nationwide Investigation

Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome

Aromatic Characteristics of Passion Fruit Wines Measured by E-Nose, GC-Quadrupole MS, GC-Orbitrap-MS and Sensory Evaluation

Contact Info

Product

Resources

About