Trauma to the anterior teeth can lead to pulp necrosis and subsequent periapical lesions. Most of the cases remain undetected unless found in an IOPAR, the tooth gets discoloured or gets secondarily infected. In such cases, non-surgical endodontic therapy can be done as the first line of management with regular follow up. Surgical approach is indicated only if the non- surgical approach becomes a failure. A series of two cases with large periapical lesion following trauma to the maxillary anteriors were treated with multivisit non –surgical endodontic therapy. Inter-appointment dressings were given. Patients were recalled for evaluation of healing. Six months follow up radiographs showed healing of the lesion with significant increase in the radiopacity suggestive of bony healing. For the treatment of periapical lesions, non-surgical endodontic therapy should be considered as first line treatment option as it proves to be a more conservative approach.