Non-suicidal self-injury and electroconvulsive therapy: Outcomes in adolescent and young adult populations

Rootes-Murdy, Kelly; Carlucci, Marianna; Tibbs, Michael; Wachtel, Lee E.; Sherman, Martin F.; Zandi, Peter P.; Reti, Irving M.

doi:10.1016/j.jad.2019.02.057

Cited by 20 publications

(22 citation statements)

References 26 publications

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“…Apart from non-CORE/PRIDE, the studies above indicate that older age, male, and with baseline cognitive decline were predictors of a preferable response and less likelihood of a relapse (Socci et al, 2018;van Diermen et al, 2018). Contrariwise, depressed individuals who were young, female, and with a history of non-suicidal self-injury were more likely to be resistant to ECT (Socci et al, 2018;Rootes-Murdy et al, 2019). In addition, ultrabrief may not be superior to brief-pulse ECT in symptom improvement, but memory disturbance was less reported (Bjoerke-Bertheussen et al, 2018;Martin et al, 2019).…”

Section: Clinical Observation By Questionnaire Assessmentsmentioning

confidence: 98%

“…In relation to suicide, large-scale nationwide studies performed retrospectively indicate that in patients with unipolar disorder and bipolar depression, ECT had superior anti-suicidal effects (Liang et al, 2018). However, for adolescent and young adult females with a history of non-suicidal self-injury, lower odds of response and remission and great mean times of treatment were observed (Rootes-Murdy et al, 2019).…”

Section: Clinical Observation By Questionnaire Assessmentsmentioning

confidence: 99%

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Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism

Yao

Sun

et al. 2020

Front. Psychol.

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Depression is one of the most common disorders causing mortality around the world. Although electroconvulsive therapy (ECT) is, along with antidepressants and psychotherapy, one of the three major treatments of depression, it is still considered as the last resort for depressed patients. This situation is partially due to limited studies and uncertainty regarding its mechanism. However, decades of increased research have focused on the effects of ECT on depression and its potential mechanism. Furthermore, these investigations may suggest that ECT should be a first-line therapy for depression due to its profound effects in relieving desperation in certain situations. Here, we outline recent clinical and preclinical studies and summarize the advantages and disadvantages of ECT. Thus, this review may provide some hints for clinical application.

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Section: Clinical Observation By Questionnaire Assessmentsmentioning

confidence: 98%

Section: Clinical Observation By Questionnaire Assessmentsmentioning

confidence: 99%

Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism

Yao

Sun

et al. 2020

Front. Psychol.

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“…Electroconvulsive therapy (ECT) may be seen as a safe and effective modality for treatment-refractory psychiatric disorders in adolescents as in adults [ 76 ]. Possible effectiveness has been shown for depression in youth [ 77 ], and non-suicidal self-injury in female adolescents [ 78 ]. However, there are no published randomized controlled trials of ECT yet [ 76 , 78 ].…”

Section: Diagnostic and Therapeutic Issues Regarding Tribmentioning

confidence: 99%

“…Possible effectiveness has been shown for depression in youth [ 77 ], and non-suicidal self-injury in female adolescents [ 78 ]. However, there are no published randomized controlled trials of ECT yet [ 76 , 78 ]. A review regarding repetitive transcranial magnetic stimulation (rTMS) for adolescents with treatment-resistant depression reports that rTMS might have some benefit for these youths.…”

Section: Diagnostic and Therapeutic Issues Regarding Tribmentioning

confidence: 99%

Treatment Refractory Internalizing Behaviour Across Disorders: An Aetiological Model for Severe Emotion Dysregulation in Adolescence

Herpers

Neumann

2020

Child Psychiatry Hum Dev

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Auto-aggressive behaviour, especially treatment refractory suicidality in adolescents with psychiatric disorders, may be challenging to clinicians. In search of therapeutic possibilities, we have integrated current opinions regarding causality and interdependency of suicidality and auto-aggressive behaviour across disorders within the HiTOP framework. We propose a developmental model regarding these unsettling behaviours in youths that may help to guide future directions for research and interventions. We argue that the interdependent development of biologic factors, attachment, moral reasoning and emotion regulation in an overprotective environment may lead to social anxiety and later during development to emotion dysregulation and severe internalizing behaviour disorders. To optimize treatment efficacy for both internalizing and externalizing behaviour, we emphasize the importance transdiagnostic interventions, such as addressing non-compliance, restoration of trust between parents and their child, and limitation of avoidance behaviour. These may be seen as higher order interventions within the HiTOP framework.

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“…Such patients typically have serious, complicated psychiatric histories, with multiple comorbidities. Their primary illness is not a mood or psychotic disorder, but is rather more driven by personality, psychosocial and environmental issues; for them, ECT may not be an appropriate option (4,5). They need intensive, ongoing multimodal psychiatric care, typically with medication combinations and psychotherapy, but not usually ECT.…”

mentioning

confidence: 99%